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Background Diabetes mellitus has been identified as one of the major contribution of mortality worldwide. A comparative intervention (concurrent control) study was conducted to determine the influences of pharmaceutical care on quality of life in Type II diabetic patients. Materials and Method The study was carried out at the outpatient clinic of Hospital Kuala Lumpur, Malaysia for five months by convenience sampling where 140 patients were enrolled equally into control and intervention groups. Intervention group received counseling with information leaflet whereas control group was deprived of any pharmaceutical care till the end of the study. Follow up was done one month after baseline by telephone survey. Pre-validated Diabetes-39 questionnaire was administered at baseline and follow up. Clinical parameters such as fasting blood glucose, body mass index and HbA1c were compared between groups post counseling. Results Independent t-test and Chi-square test were conducted and intervention group showed a reduction in the effect of diabetes on quality of life. The changes in mean score was highest in energy and mobility domain, showing a decline from 56.53±17.80 at baseline to 49.57±17.12 at follow up (p<0.05). The clinical parameters revealed slight reduction in intervention group. However, the differences were not significant (p>0.05). There were no significant changes in scores and clinical outcomes for control group (p>0.05). Three domains were negatively associated with quality of life where energy and mobility has the strongest association. Conclusion The findings revealed that the intervention program was effective in enhancing Type II Diabetes patients' quality of life.



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