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A VERY SEVERE DERMOPATHY AND OPHTHALMOPATHYIN PATIENTS WITH AUTOIMMUNE THYROID DISEASE: CASE REPORT AND LİTERATÜRE REVIEW

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2004

Key Words:

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Although ophthalmopathy (most commonly) and dermopathy (uncommon) are the extrathyr-oidal manİfestations of Graves' disease, they are extremely rare in Hashimoto's thyroiditis. We present a case of Hashimoto's hypothyroidism with ophthalmopathy and dermopathy (the elephantiasic form of pretibial myxedema) in a 46-year-oİd man. He was diagnosed as having Hashimoto's hypothyroidism with decreased thyroİd hormone levels and elevated TSH, anti-thyroid peroxİdase and antithyroglobulin anübodies levels, and on palpation the thyroid gland was typİcal for Hashimoto's thyroiditis. The patient had infiltrative ophthalmopathy and eleph-antiatic form of pretibial myxedema. Thyroid ultrasound revealed that the parenchyma was heterogenous. Urinary glycosaminoglycans level was increased. Orbital CT scanning showed that extraocular muscles were thickened indicating the infiltrative opthalmopathy. This case demonstrates the uncommon extrathyroidal manifestation (a very severe dermopathy and ophthalmopathy) of autoimmune thyroid disease.
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  • 2
109-112
  • English

REFERENCES

References: 

1. Bahn RS, Garrity JA, Bartley GB, Gorman CA. Diagnos-lic evaluation of Graves' ophthalmopathy. Endocrinol Metab Clin North Ame 1988; 17:527-545.
2. Fatourechi V, Pajouchi M& Fransway AF. Dermopathy of Graves' disease (pretibial myxedema): revievv of 150 cases. Medicine 1994;73:1-7.
3. HoriuchiY. Pretibial myxedema associated with chronic thyroiditis. Arch Dermato! 1985; 121:451.
4. Fisher DA, Pandian MR, Carlton E. Autoimmune thyroid disease: an expandîng spectrum. Pediatr Clin North Am 1987; 34:907-918.
5. Burch HB, VVartofsky L. Graves' ophthalmopathy: cur-rent concepts regarding pathogenesis and management. Endocrinol Rev 1993; 14:747-793.
6. ' Marcocci C, Bartalena L, Bogazzi F, Panicucci M, Ptn-
chera A. Studies on the occurrence of ophthalmopathy in Graves' disease. Açta Endocrinol 1989; 120:473-478.
7. Brownlie BE, Newton OA, Singh SP. Ophthalmopathy associated vvith primary hypothyroidism. Açta Endocrinol 1975; 79:691-699.
8. Kriss JP. Pathogenesis and trcatment of pretibial myxe-dema. Endocrinol Metab Clin North Am 1987; 16:409¬415.
9. Kahaly G, Schuiler M, Sevvell AC, ei ali. Urinary glyco-samİnoglycans in Graves' ophthalmopathy. Clinical En-docrinoiogy 1990; 33:35-44.
İ0. Schwar(z KM, Fatourechi V, Ahmed DDF, Gregory RP. Dermopathy of Graves' disease (pretibial myxede-ma):long-term oııtcome. J Clin Endocrinol Metab 2002; 87:435-446.
11. Cronin CC, Higgins TM, Murphy Ferriss JB. Concomitant Graves1 disease and Hashimoto's thyroiditis, present-ing as primary hypothyroidism Ir Med J 1996; 89:141¬142.
12. Singh SK, Singh KK, Sahay RK. Hashimoto's Thyroiditis vvith Orbitopathy and Dermopalhy. J Postgradııale Medicine "Images in Medicine" 2000; 46 (4).
13. Schvvartz K.M, Fatourechi V, Ahmed DDF, Pond GR. Dermopathy of Graves' Disease (Pretibial Myxedema): Long-Term Outcome. J Clin Endocrinol Metab 2002; 87:438^(46.
14. Fatourechi V, Pajoııhİ M, Fransvvay AF. Dermopathy oİ Graves' disease (pretibial myxedema). Revievv of İ50 cases. Medicine 1994;73:1-7.
15. Wyse EP, McConahey WM, VVoolncr LB, Sciıolz DA, Kearns TP. Opthalmopathy vvitout hyperthyroidism in patienls vvith histological Hashimoto's Ihyroîdİfıs. J Clin Endocrinol Metab 1968;28:1623-1629.

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