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ÜROGENİTAL SİSTEME METASTAZ YAPAN İKİ MEME KARSİNOMU OLGUSU

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Abstract (2. Language): 
Two cases ofbreast carcinoma metastatic to the kidney and the bladder. Isolated kidney and bladder metastases of breast carcinoma after a long disease free interval are very rare. We re-port on two cases of breast carcinoma metastatic to the kidney and the bladder after a disease-frec interval of 12 and 24 years, respeetively. Morphology of the tumors on frozen and sucece-ding paraffin block section analysis of an incİdental kidney lesion of 55-year-oîd-wonıan and a bladder wall mass of a 65-year-old-woman complaining hematuria, and the medical history of the first patİent revealed breast carcinoma, and diagnoses were confirmed by iınmunohistoche-mical studies shov/ing tumor cells were reactive for GCDFP-15, estrogen and progesterone re-ceptor antibodies. There were no other organ metastases.
Abstract (Original Language): 
Meme kai'sinomunun uzun hastalıksız döneminden sonra tespit edilen izole böbrek ve mesane metastazları enderdir. Çalışmamızda 12 ve 24 yıllık hastalıksız dönemden sonra sırası ile böbrek ve mesane metastazı yapan 2 meme karsinomu olgusu sunulmaktadır. Ellibeş yaşındaki kadın hastanın insidental olarak saptanan böbrek ve hematürili 65 yaşındaki kadın hastanın mesane duvarındaki kitlelerinin frozen ve ardından parafin blok kesitlerinin ayrıntılı İncelenmesinde izlenen tümör morfolojisi, İlk vakada bilinen hasta öyküsü ile meme karsinomu metastazı düşünülerek yapılan immunbistokimyasal incelemede lümör hücrelerindeki GCDFP-15 (gross eystic disease fluid protein), östrojen ve progesteron reseptör antikor reaktiviteleri ile tanılar doğrulandı. Olgularda başka organ metastazı saptanmadı.
300-304

REFERENCES

References: 

(. Bates AW, Buitlıım SI: Seetmdary neoplasıııs of the bladder a re histological mimics of nonlransitional celi primary tumours: clinicopadıological and histological features of 282 cases. Histopathology 36:32 (2000).
2. Grignon DJ, Eblc JN: Rcnal neoplasms. In Jenııette JC, Olson JL, Schwartz MM, Silva FG (eds). Heptinstali's Pathology of the Kidney, 5lh cd, Lippincott-Raven, pp:1541 (1998).
3. Juan R, Breast. In: Juan R.editor. Ackerman's Sıırgical pathology. 8lh ed. Mosby; p.I565 (1999).
4. Mazeman E, Wcmeau L, Lemaitre G, Kozireff P: Secon-dary tumors of the kidney. J Urol Nephrol 82: 145 (1976).
5. Perez-Mesa C, Pickren JW, Woodruff MN, Mohallatee A: Metastatic carcinoma of fhe urinary bladder from primary tumors in the mammary gland of female patients. Surg Gynecol Obstet 121:813 (1965).
6. RidJon HC, McAdams GB: Breast carcinoma metastatic to kidney. J Urol 98:328 (1967).
7. Silverstein LI, Plaine L, Davis JE, Kabakow B: Breast carcinoma metastatic to bladder. Urology 29:544 (1987).
8. Takehara K, Koga S, Nishikİdo M, et al. Breast cancer metastatic to the kidney. Anticancer Res. 19:5571 (1999).

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