Buradasınız

Anasayfa » Content

Tiroid lezyonlarmda tiroid ince iğne aspirasyon biyopsisi ve histopatoloji sonuçlarının karşılaştırılması

The comparison of fıne needle aspıratıon bıopsy and hıstopathology results ın thyroıd lesıons

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2006

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The comparison of fıne needle aspıratıon bıopsy and hıstopathology results ın thyroıd lesıons Purpose: To determine the utility of fine needle aspiration biopsy (pNAB) in the evaluation of thyroid lesions at our faculty by comparing the results of pNAB and pathology report results of the patients who underwent surgery. Patients and Method: We compared the cytologic and histopathologic results of 83 patients who underwent thyroidectomies after pNAB at the Suleyman Demirel University School of Medicine between 2002 and 2005. pNAB results were categorized as benign, suspicious for malignancy, malign and insufficient. Results: The diagnosis of pNAB of 83 cases were benign, insufficient, suspicious for malignancy and malign in 45(54.2%), 26(31.3%), 8(9.6%), 4(4.8%) cases respectively. five of cases which was cytologically diagnosed as benign, 2 of cases which was cytologically diagnosed as suspicious for malignancy and 1 of case which was cytologically diagnosed as malign were found to be malign histologically. Sensitivity, specificity, accuracy, false-positivity, false-negativity, positive predictive value and negative predictive value were 37.5% 81.6%, 75.4%, 18.3%, 62.5%, 25% and 88.8%, respectively. When the incidental papillary microcarcinomas excluded sensitivity, specificity, accuracy, false-positivity, false-negativity, positive predictive value, negative predictive value were changed to 75%, 81.6%, 81.1%, 18.3%, 25%, 25%, 97.5%, respectively. Conclusion: pNAB is a valuable diagnostic method in the evaluation of thyroid lesions when papillary microcarcinomas excluded.
Bookmark/Search this post with
Abstract (Original Language): 
Amaç: Tiroid ince iğne aspirasyon biyopsi (İİAB) sonuçları ile opere edilen olguların patoloji rapor sonuçları karşılaştırılarak, tiroid lezyonlarının değerlendirilmesinde fakültemizde İİAB'lerinin etkinliğinin saptanması. Hastalar ve Metod: SDÜ Tıp fakültesinde 2002-2005 yılları arasında İİAB sonrası tiroidektomi yapılan 83 hastanın sitoloji ve histopatoloji sonuçları karşılaştırıldı. İİAB sonuçları benign, malignite kuşkulu, malign ve yetersiz olarak sınıflandırıldı. Bulgular: Seksen üç İİAB materyalinin 45'i (%54.2) benign, 26'sı (%31.3) yetersiz, 8'i (%9.6) malignite kuşkulu, 4'ü (%4.8) maligndir. Sitoloji sonucu benign olarak değerlendirilen olguların 5'i, malignite kuşkulu olarak değerlendirilen olguların 2'si ve malign olarak değerlendirilen olguların 1'i histolojik olarak maligndir. Çalışmamızda duyarlılık %37.5, özgüllük %81.6, tanı değeri %75.4, yanlış pozitiflik değeri %18.3, yanlış negatiflik değeri %62.5, pozitif prediktif değeri %25, negatif prediktif değeri %88.8'dir. İnsidental papiller mikrokarsinom tanısı alan olgular dışlandığında duyarlılık %75, özgüllük %81.6, tanı değeri %81.1, yanlış pozitiflik değeri %18.3, yanlış negatiflik değeri %25, pozitif prediktif değeri %25, negatif prediktif değeri %97.5 olarak bulundu. Sonuç: İİAB, tiroid lezyonlarının değerlendirilmesinde papiller mikrokarsinom tanısı dışlandığında değerli bir tanı yöntemidir.
FULL TEXT (PDF): 
PDF icon arastirmax-tiroid-lezyonlarmda-tiroid-ince-igne-aspirasyon-biyopsisi-histopatoloji-sonuclarinin-karsilastirilmasi.pdf
  • 4
27-31
  • Turkish

REFERENCES

References: 

1. Ashcraft MW, Van Herle AJ. Management of thyroid nodules II: scanning techniques thyroid suppressive therapy and fine-needle aspiration. HeadNeck Surg 1981;3:297-322.
2. Boring CC, Squires TS, Tong T. Cancer statistics 1993. CA CancerJClin 1993;43:7-26.
3. Burch HB, Burman KD, Reed HL, Buckner L, Raber T, Ownbey JL. Fine needle aspiration of thyroid nodules determinants ofinsufficiency rate and malignancy yield at thyroidectomy. Acta Cytol 1996;40:1176-1183.
4. Silverman JF, West LR, Larkin EW, Park KH. The role of fine needle aspiration biopsy in the rapid diagnosis and management ofthyroid neoplasm. Cancer 1986;57:1164-1170.
5. Caraway NP, Sneige N, Saman NA. Diagnostic pitfalls in thyroid fine-needle aspiration: a review of 394 cases. Diagn Cytopathol 1993;9:345-350.
6. Harach HR, Zumsan SB. Cytologic findings in the follicular variant ofpapillary carcinoma of
the thyroid. Acta Cytol 1992;36:142-146.
7. Sidawy MK, Del Vecchio DM, Knoll SM. Fine-needle aspiration ofthyroid nodules: correlation between cytology and histology and evaluation ofdiscrepant cases. Cancer 1997;81:253-259.
8.
Sar
ı A, Çetin R, Sarı M, Çandır Ö. Tiroid lezyonlarının değerlendirilmesinde ince iğne aspirasyon biyopsisinin yeri. SDÜ Tıp Fakültesi Dergisi 1998;5(4):139-143.
9. Singer PA. Evaluation and management ofthe solitary thyroid nodule. Otolaryngol Clin North Am 1996;29:577-579.
10. Gharib H, Goellner JR. Fine needle aspiration biopsy ofthe thyroid: an apprasial. Ann Intern Med 1993;118:282-289.
11. Demicco C. Assessment and prospects ofthyroid cytology. Ann Endocrinol 1993;54:258-263.
12. Mandreker SRS, Nadkarni NS, Pinto RGW, Menesez S. The role offine needle aspiration cytology as the initial modality in the investigation ofthyroid lesions. Acta Cytol 1995;39:898-904.
13. Rios A, Rodriguez JM, Galindo PJ, Montoya M, Tebar FJ, Sola J, Canteras M, Parrilla P. Utility
of fine-needle aspiration for diagnosis of carcinoma associated with multinodular goitre. Clin Endocrinol 2004;61:732-737.
14. Berner A, Pradhan M, Jorgensen L, Heilo A, Groholt KK. Fine needle cytology ofthe thyroid gland. Tidsskr Nor Laegeforen 2004;124:2359-
2361.
15. Ylagan LR. Fine needle aspiration biopsy ofthe thyroid: a cytohistologic correlation and study of discrepant cases. Thyroid 2004;14:35-41.
16. Yang GCH, Liebeskind D, Messina AV. Ultrasound-guided fine-needle aspiration ofthe thyroid assessed by ultrafast papanicolaou stain: data from 1135 biopsies with a two-to six year follow-up. Thyroid 2001;11:581-589.
17. Poller DN, Ibrahin AK, Cummings MH, Mikel JJ, Boote D, Perry M. Fine needle aspiration of the thyroid. Cancer 2000;90:239-244.
18. Gharib H. Fine needle aspiration biopsy ofthyroid nodules: advantages, limitations and effect. Mayo ClinProc 1994;69:44-49.
19. Buley ID. Thyroid gland. In: Gray W, McKee GT. Diagnostic cytopathology (2nd Ed)
London, Churchill Livingstone, 2003; 577-602.

Thank you for copying data from http://www.arastirmax.com