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Laparaşkopik Kolesistektomide Granisetron ve Granisetron-Droperidol Kombinasyonunun Postoperatif Bulantı Kusma Üzerine Etkileri

Effect of Granisetron and Granisetron Plus Droperidol on Postoperative Nausea And Vomıiting in Laparoscopic Cholecystectomy

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
The aim of this study was to evaluate the effects of two different anesthetic techniques on postoperative recovery and the effectiveness ofprophylactic granisetron and granisetron plus droperidol for the preventing of postoperative nausea and vomiting (PONV) in 60 patients who were undergone elective laparoscopic cholecystectomy. Induction of anesthesia was induced with propofol + fentanyl + atracurium IV, maintained with propofol infusion in group P (n:30) and induced with thiopentone + fentanyl + atracurium IV, maintained with sevoflurane in group S (n:30). Group P and group S were divided into two subgroups for prophylaxis of PONV. Group P-G and group S-G received 3 mg granisetron, group P-GD and group S-GD received 3mg granisetron + 1.25 mg droperidol IV just before induction. Prophylaxis of PONV provided almost complete effectiveness in the patients who received granisetron + droperidol.
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Abstract (Original Language): 
Elektif laparoskopik kolesistektomi planlanan 60 olguda postoperatif bulantı kusma (POBK) profil aks is inde granisetron ve granisetron-droperidol kombinasyonunun etkinliğini araştırmayı amaçladık. Tüm olgularda anestezi indüksiyonu 5 mg/kg tiyopenton, 2 mikrogram/kg fentanil, 0.5 mg/kg atrakuryum ile, idame % 2-2.5 konsantrasyonda sevofluran ile sağlandı. Olgular rasgele iki gruba ayrıldı. Grup G (n: 30) olgulara indüksiyondan hemen önce 3 mg granisetron; Grup GD (n: 30) olgulara 3 mg granisetron ve 1.25 mg droperidol İV verildi. Granisetron-droperidol kombinasyonu kullanılan olgularda POBK profilaksisi tama yakın etkinlik sağlarken, yalnız granisetron kullanılan olgularda POBK sıklığı daha fazla olarak saptandı.
FULL TEXT (PDF): 
PDF icon arastirmax-laparaskopik-kolesistektomide-granisetron-granisetron-droperidol-kombinasyonunun-postoperatif-bulanti-kusma-uzerine-etkileri.pdf
  • 1
23-25
  • Turkish

REFERENCES

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