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Epinefrin Ve Soğuk Stresi Uygulamasının Bazı Serum Biyokimya Parametreleri Üzerine Etkileri

Effects Of Epinephrine And Cold Stress On Some Serum Biochemical Parameters

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Abstract (2. Language): 
In this research, effects of not only acute cold stress treatment but also epinephrine administration, used as a treatment peptide, on some serum components were investigated comparatively. According to the analysis results, it was measured that there was a decrease in the level of serum total protein and cholesterol but there was an increase in the level of triglyceride and glucose in rat groups that were exposed to cold stress and epinephrine administration. Therefore, exogenous epinephrine treatment (1 mg/kg) and cold stress application in 48 hours at 8 °C effect carbohydrate and lipid metabolism on rats. Thus, this can be evaluated as an implication that homeostatic balance might be conserved.
Abstract (Original Language): 
Bu çalışmada gerek akut soğuk stresi uygulamasının gerekse tedavi amaçlı olarak da kullanılan epinefrin uygulamasının bazı serum bileşenleri üzerine etkileri karşılaştırmalı olarak araştırıldı. Analiz sonuçlarına göre; hem epinefrin uygulama grubu sıçanların hemde soğuk stresine maruz bırakılan sıçanların serumlarında total protein ve kolesterol seviyesinde azalma, glukoz ve trigliserit seviyesinde ise artış kaydedildi. Sıçanlara eksojen epinefrin verilmesi (1mg/kg; ip) ve 48 saat 8°C soğuk stresi uygulamasının karbohidrat ve lipit metabolizmasını etkilediği böylece homeostazisin korunmaya çalışıldığı anlaşıldı.
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