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Flow Sitometri ile DNA İçerik ve Proliferasyon Aktivitesi Ölçümlerinin Prognostik Faktör Olarak Onkoloji Alanında Uygulanması

The application of DNA content and proliferation activity measurements with lion cytometry as prognostic factor in oncology field

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1996

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Flow Cytometry (FC) is a technique that gives permission to measure several cellular features in a short time. FC has diagnostic and prognostic importance in oncology field. The measurement DNA content and proliferation activity is very easy with FC. In general aneuploid cell populations as well as diploid cell populations with a high proliferative component <S+ G2M) correlate with a more adverse prognosis in a number of malignancies. In this study the relationship between DNA content proliferation activity and prognosis on different cancer types are reviewed.
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Abstract (Original Language): 
Flow Sitometri bir çok hücresel özelliği, kısa bir zamanda, objektif olarak ölçmeye izin veren bir tekniktir. Onkoloji alanında Flow Sitometri diagnostik ve prognostik öneme sahiptir. Flow Sitometri ile DNA içerik ve proliferasyon aktivitesi ölçümleri yapmak oldukça kolaydır. Genel olarak anöploid hücre popülasyonları veya yüksek proliferasyon komponentli (S-+G2M) diploid hücre popülasyonları malign olguların çoğunda kötü prognozla korelasyon göstermektedir. Bu çalışmada değişik kanser tiplerinde DNA içeriği ve proliferasyon aktiviteleri ve prognoz arasındaki ilişki yeniden gözden geçirilmiştir.
FULL TEXT (PDF): 
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  • 1
52-56
  • Turkish

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