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Değişik vücut ağırlıklarına sahip kişilerde plazma ve eritrosit içi kolinesteraz aktiviteleri ve çeşitli plazma parametre değerleri

Plasma and erythrocyte cholinesterase activities and values of some plasma parameters in subjects with different body weight

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1994

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, the aim was to show whether there is a relationship between cholinesterase activities and plasma lipid parameters in overweight, normal and lean individuals. This study were carried out on 34 female. 55 male (totally >H9) volunteers. Body Mass Indexes were calculated, and plasma glucose, triglyceride, phospholipid, total cholesterol. IIDL. LDL and basal insulin values as well as erythrocyte and plasma cholinesterase activities were determined. The plasma glucose, basal insulin, triglyceride, phospholipid levels, plasma cholinesterase activities and CRF. ERF values of overweight male subjects were found to be higher and erytrocyte cholinesterase activities to be lower than those of the other groups. In female, total cholesterol. ERF, CRF values, and plasma cholinesterase activities of overweight subjects were found to be higher and erytrocyte cholinesterase activities to be lower than those of the other groups. BMI showed significant correlations with all parameters except for IIDL levels in men and glucose, triglyceride and phospholipid values in women. In conclusion, being together with changes of the cholinesterase activities and lipid prophile changes in overweight subjects might be important in the pathologies seen in obesity. /Journal of Turgut Özal Medical Center 1(2): 126-131 .1994/
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Abstract (Original Language): 
Bu çalışmada aşırı kilolu, normal kilolu ve zayıf sağlıklı kişilerde eritrosit içi ve plazma kolinesteraz aktiviteleri ile plazma lipid parametreleri arasında ilişki bulunu/) bulunmadığını göstermek amaçlanmıştır. Çalışma 34'ü kadın. 55'i erkek. X9 gönüllü üzerinde yapıldı, l'ücut kille indeksi (BMI) hesaplandı. Plazma glukoz. bazal insulin, triglıserit, fosfolipid. total kolesterol. IIDL. I.DL değerleri ve eritrosit içi (EACIIE) ve plazma kolinesteraz (PCHE) aktiviteleri tayın edildi. Aşırı kilolu erkeklerin glukoz. bazal insulin, trigliserit. fosfolipid. PCI IE. ERİ''. CRF değerleri ve l.DL IIDL oranı diğer grupların değerlerinden yüksek. EACH E değerleri düşük bulundu. Bayanlarda ise aşırı kiloluların total kolesterol. PCI IE. CRF. ERh' değerleri diğer grupların değerlerinden yüksek. EACIIE değerleri düşüktü. Erkeklerde IIDL. bayanlarda glukoz. trigliserit ve fosfolipid hariç, bütün parametrelerle BMI arasında anlamlı ilişki bulundu. Aşırı kilolu kişilerde lipid profiline kolinesteraz aktivitesı değişikliklerinin eşlik etmesinin, obesite ile birlikte olan patolojilerin oluşumunda önemli olabileceği sonucuna varıldı. / Turgut Özal Tıp Merkezi Dergisi I(2): 126-131 .1994/
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PDF icon arastirmax-degisik-vucut-agirliklarina-sahip-kisilerde-plazma-eritrosit-ici-kolinesteraz-aktiviteleri-cesitli-plazma-parametre-degerleri.pdf
  • 2
126-131
  • Turkish

REFERENCES

References: 

1. Rodwell VW. Enzymes: General Properties. In: Murray RK, Granner DK, Mayes PA, Rodwell VW, eds. Harper's Biochemistry. 22nd ed. Lebanon: Appleton-Lange. 1991;58-67.
2.Öz OY, Gökbel H, Büyükbaş S, Tamer N. Kolinesteraz ve klinik önemi. S Ü Tıp Fak Derg 1992,8:325-8.
3. Ganong WF. Review of medical physiology. 15th ed. USA: Appleton-Lange. 1991:90-246
4. Chu MU, Fontaine P, Kutty KM, Murphy D, Redheendran R. Cholinesterase in serum and low density lipoprotein of hyperlipidemic patients. ClinChim Acta. 1978;85: 55-9.
5. Kutty KM, Jain R, Huang SN, Kean K. Serum pseudocholinesterase: High density lipoprotein/ cholesterol ratio as an index of risk for cardiovascular disease. Clin Chim Acta 1981; 115. 55-61.
6. Jain R, Kutty KM, Huang SN, Kean K. Pseudocholinesterase/high density lipoprotein cholesterol ratio in serum of normal persons and of hyperlipoproteinemics. Clin Chem 1983; 29:1031-3.
7 Kutty KM, Redheendran N, Murphy D. Serum cholinesterase function in lipoprotein metabolism. Expenentia 1977; 33:420-3.
8 Lewis PJ, Lowing RK, Gomperta D. Automated discrete kinetic method for erythrocytes acetylcholinesterase and plasma cholinesterase. Clin Chem 1981;27:926-29.
9. Casimirri F, Pasquali R, Cantobelli S, Melchionda N, Barbara L. Obesity and adipose tissue distribution in men: relation to sex steroids and insulin. Minerva Endocrinol 1991;16:31-5.
10 Dietz WH. Obesity. Am Coll Nutr 1989;8.13S-21S.
11 Burke GL, Weber LS, Sirinivasan SR. et al. Fasting plasma glucose and insulin levels and their relationship to cardiovascular risk factors in children. Metabolism 1986;35:441-6.
12. Bray GA, Gray DS. Obesity. Part I-Pathogenesis. West J Med 1988;149:429-41.
13. Peiris AN, Gustafson AB, Kissebagh AH. Health and regional adiposity: implications for the clinician. Year Book of Endocrinol 1990;283-99.
14 Evans DJ, Hoffmann RG, Kalkhoff RK, Kissebah AH. Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women. Metabolism 984; 33:68-75.
15 Baynes C, Henderson AD, Anyaoku V, Richmond W, Johnston DG, Elkeles RS. The influence of regional adiposity on atherogenic risk factors in men
and women with type 2 diabetes. Diabetic Med 1991;8:458-63.
16 Chaine G, Cormier L, Moutillet M, Noreau L, Leblanc C, Landry F. Body Mass Index as a discriminant function among health-related variables and risk factors. J Sports Med Phys Fitness 1989; 29: 253-61.
17. Haffner SM, Fong D, Hazuda HP, Pugh JA, Patterson JK. Hyperinsulinemia, upper body adiposity and cardiovascular risk factors in non-diabetics. Metabolism 988; 37:338-45.
18. Seidell JC, Cigolini M, Deurenberg P, Oosterlee A, Doornbos G. Fat distrubition, androgens, and metabolism in nonobese women. Am J Clin Nutr 1989; 50:269-73.
19. Herz F, Kaplan EA. Human erythrocyte acetylcholinesterase. Pediatr Res 1973;7:204-14.
20. Cucuianu M, Opincaru A, Tapalaga D. Similar behavior of lechitin: cholesterol acyltransferase and pseudocholinesterase in liver disease and hyperlipoproteinemia.Clin Chim Acta 1978;85:73-9.
21. Kutty KM, Huang SN,Kean KT. Pseudocholinesterase in obesity. Hypercaloric diet induced changes in experimental obese mice. Experientia 1981;37:1141-2.
22. Kutty KM, Rowder G, Cox AR Interrelationship between serum p lipoprotein and cholinesterase. Can J Biochem 1973;51:883-7.
23.Öz OY, Akkuş İ, Büyükbaş S, Gökbel H, Bayram A, Gök H, Türk S, Erdoğan Y. Koroner kalb hastalarında plazma ve eritrosit içi kolinesteraz aktivitelerınin ve PCHE/HDL (CRF), EACHE/HDL (VRF) oranlarının araştırılması. S Ü Tıp Fak Derg 1992; 8:435-9.
24. Garrow JS. Obesity. In: Cohen RD, Lewis B, Alberty KGM, Dermas AM, editors.The metabolic and molecular basis of acquired disease. London: WB Saunders. 1990: 583-601.

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