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Omega-3 ve omega-6 yağ asitlerinin özellikleri, etkileri ve kardiyovasküler hastalıklar ile ilişkileri

Properties, functions of omega-3 and omega-6 fatty acids and relationship between essential fatty acids and cardiovasculer diseases

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DOI: 
doi:10.2399/tahd.08.121
Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Essential fatty acids (EFAs) are essential for survival of humans and other mammals, and they can not be synthesized in the body; hence, they have to be obtained by the diet. There are two types of naturally occurring EFAs in the body, the omega-6 (co-6) series derived from cis-linoleic acid and the omega-3 series (co-3) derived from a-linolenic acid (ALA, 18:3). co-3 and co-6 fatty acids display a variety of beneficial effects on various organ systems and diseases. The metab¬olism of EFAs is altered in several diseases such as obesity, hyperten¬sion, diabetes mellitus, coronary heart disease, schizophrenia, Alzheimer's disease, atherosclerosis, and cancer. In this paper, we review both the structure properties and metabolisms of fatty acids and the relationship between EFAs and cardiovascular diseases.
Abstract (Original Language): 
Esansiyel yağ asitleri (EYA) insan ve diğer memelilerde yaşam için mutlak gerekli olan ve vücutta sentezlenemediğinden diyetle alınması gereken yağ asitleridir. Vücutta doğal olarak iki tipi bulunur. Omega-6 (co-6) serisi cis-linoleik asitten, omega-3 (co-3) serisi a-li-nolenik asitten kaynaklanır. co-3 ve co-6 yağ asitlerinin çeşitli organ ve hastalıklarda yararlı etkileri bulunur. EYA metabolizması obezi-te, hipertansiyon, diyabetes mellitus, koroner kalp hastalıkları, şizofreni, Alzheimer hastalığı, ateroskleroz ve kanser oluşumunda değişir. Bu derlemede yağ asitlerinin yapısal özellikleri ve metabolizmaları ile kardiyovasküler hastalıklarla ilişkileri gözden geçirilmiştir.
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