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MEMBRANOPROLÎFERATÎFGLOMERÜLONEFRÎTÎ VE MÎNÎMAL LEZYON HASTALIĞI OLAN ÇOCUKLARDA TÎROÎD FONKSÎYONLARI

THYROID FUNCTIONS IN CHILDREN WITH MINIMAL CHANGE NEPHROTIC SYNDROME (MCNS) AND MEMBRANOPROLIFERATIVE GLOMERULONE PHRITIS (MPGN) IN RELAPS AND REMISSION

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1996

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Triiyodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH) and serum albumin concentrations were measured in 49 children. 23 of them were MCNS (12 in relapse, 11 in remission), 26 of them were MPGN(13 in remission). T3 and T4 were significantly lower and TSH was significantly higher in relapse when compared with remission in both groups. There were no significant differences in serum albumin, T4 and TSH concentrations in remission between the two groups. However, the albumin levels of patients with MCNS showed a positive correlation with T3. There was no correlation with albu¬min and T4, or albumin and TSH. Neither could we find any correlation between T3, T4 and TSH levels with albumin in patients with MPGN.
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Abstract (Original Language): 
12 rölapsta minimal lezyon hastalığı (MLH), 11 remisyonda MLH, 13 rölapsta membranoproliferaüf glomerülonefritli (MPGN) ve 13 remisyonda MPGN' li hastanın serum albumin, triiyodotironin (T*), tiroksin (Tj) ve tiroid stimülan hormon (TSH) düzeylerine bakıldı. Her iki grupta da rölaps döneminde remisyon dönemine göre To ve T* belirgin düşük TSH ise belirgin olarak yüksek bulundu. Ancak istatistiksel fark MLP gruubunda tüm parametrelerde p<0,0001 iken MPGN grubunda p<0,05 idi. Remisyonda, iki grup arasındaki albumin, T*, TSİ I farksızdı. Yaş ortalaması daha küçük olan MLH' da remisyonda serum Tj ortalamaları yüksek iken rölapsta tiroidfonksiyonla-n,MLH grubunda MPGN grubundan belirgin olarak düşüktü. Rölapsta tiroid fonksiyonlarındaki değişken¬liğin serum albümin düzeyi ile korelasyonuna bakıldı¬ğında sadece MLH' da serum albümin azalması ile T* azalması anlamlı bulunurken diğerleri anlamsız bu¬lundu.
FULL TEXT (PDF): 
PDF icon pdf_tndt_142.pdf
  • 2
85-87
  • Turkish

REFERENCES

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