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Serum Total and Free Calcium in Hypertension

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Abstract (2. Language): 
Introduction: Hypertension is a chronic condition of concern due to its role in causation of coronary heart disease, stroke and other vascular complications. Calcium metabolism is supposed to be linked with the pathophysiology of hypertension, and various studies have shown mixed results. The present study was planneo measure serum total and free calcium levels in hypertensive patients. Settings and Design: A case-control study involving 80 subjects. Subjects were grouped into 40 healthy controls and 40 cases of hypertension. Results: Both serum total and free calcium levels were decreased, in hypertensive subjects as compared to controls. Conclusions: Decreased serum calcium levels suggest that calcium plays a crucial role in the pathogenesis of hypertension.
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716-720

REFERENCES

References: 

1. Thomas A. Gaziano, J.Michael Gaziano. Epidemiology of Cardiovascular disease. In:Longo, Fauci,
Kasper, Hauser, Jameson,Loscalzo, editor .Harrison’s Principles of Internal Medicine, 18th
ed.USA:McGrawHill Companies; 2012. p.1811.
2. Robinson BF. Altered calcium handling as a cause of primary hypertension. J Hypertens 1984;2:453-60.
3. D C Hatton, D A McCarron. Dietary calcium and blood pressure in experimental models of hypertension.
A review. Hypertension 1994;Apr,23(4):513-30
4. David B Endres, Robert K Rude. Mineral and Bone Metabolism. In:Carl A Burtis, Edward Ashwood,
Daveis Bruns,editors. Tietz Textbook of Clinical Chemistry, 4th ed.Missouri:Saunders; 2006.p. 1893.
5. Aaron R.Folsom, Charles L.Smith, Ronald J, Prineas, and Richard H Grimm,Jr. Serum Calcium Fractions
in Essential Hypertensive and Matched Normotensive subjects. Hypertension 1986; 8: 11-15
6. Tillman DM, Semple PF. Calcium and magnesium in essential hypertension. Clin Sci
(Lond).1988;Oct75(4):395-402.
7. Charumati Sabanayam , Shankar A . Serum calcium levels and hypertension among U.S. adults. J Clin
Hypertens(Greenwich) 2011;13:716-21
8. Biggs H. G., Moorehead, W.R. 2-Amino-2-methyl-1-propanol as the Alkalizing-Agent in an improved
continous-flow Cresolphthalein complexone procedure for calcium in serum. Clin Chem 1974;20:1458-60.
9. George N Bowers,Jr; Catherine Brassard, and Salvador F, Sena. .Measurement of Ionized calcium in serum
with Ion-Selective Electrodes.A : Mature technology that can meet the daily service needs. Clin Chem
1986; 32/8:1437-47
10. David A McCarron. Calcium metabolism and hypertension. Kidney International 1989; Vol. 35: 717—36
11.Garcia Zozaya JL, Padilla Viloria M, Castro A. Normotension with decreased plasma renin activity
and low serum ionic calcium levels: a prehypertensive state? South Med J. 1989; Jun 82(6):686
12. K. Sudhakar, M. Sujatha, S. Ramesh Babu, P. Padmavathi , P.P.Reddy. Serum calcium levels in patients
with essential hypertension and their first degree relatives. Indian Journal of Clinical Biochemistry
2004;19(1):21-3.
13.Kamlesh Jha, Poonam Kumari.Serum calcium in essential hypertension and its correlation with severity of
the disease. Advanced studies in Biology2011;vol.3 no.7:319-25
14. Booloo Sharma, Devajit Sarmah.Serum calcium and magnesium in patients with essential hypertension and
their first degree relatives. International Journal of Basic Medical Sciences and Pharmacy Dec 2012;vol.2 no.
2:66-9.
Indian Journal of Basic & Applied Medical Research; June 2013: Issue-7, Vol.-2, P. 716-720
720
www.ijbamr.com P ISSN: 2250-284X E ISSN: 2250-2858
15. Hazari M A, Arifuddin M S, Muzzakar S, Reddy V D. Serum calcium level in hypertension. N Am J Med
Sci 2012 Nov;4(11):569-72
16. Christina Martinez.Calcium and Hypertension.Nutrition Bytes 1998; Vol. 4 Issue 2, Article 4.

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