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Talasemi major tanisi olan hastalarda osteoporoz sikliginin degerlendirilmesi

Determination of osteoporosis frequency among the thalassemia major patients

Journal Name:

  • Türkiye Aile Hekimliği Dergisi

Publication Year:

  • 2013
DOI: 
10.2399/tahd.13.38247

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: Thalassemia major is the heaviest form of the tha-lassemias. Anemia, hepatosplenomegaly, spinal deformities and osteoporosis can be seen in the patients with thalassemia major. Our aim is to detect the frequency of osteoporosis among the tha-lassemia major patients. Methods: Patients with diagnosis of thalassemia major were included in the study. Bone mineral density (BMD) scores (T-score and Z-score) less than -2.5 were accepted as osteoporosis and the scores between -1.5 and -2.5 were accepted as osteopenia. Patients were asked if they had any treatment for bone disorders. Results: Total 25 patients with thalasemia major (14 men, 11 women) were included to study. Patients average age was 22.0± 0.90 years. According to BMD scores 16 of our patients had osteoporosis where as 9 patients had osteopenia. None of the patients were screened for osteoporosis and also none of them was taken any supportive bone treatment. Conclusions: Patients with thalasemia major should be screened for osteoporosis which will affect their further life and quality of life and appropriate medications should be given at early stages.
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Abstract (Original Language): 
Amac: Talasemilerin en agir tipi talasemi majordur. Talasemi ma-jorlu hastalarda anemi, hepatosplenomegali ve spinal deformiteler gibi kemik deformiteleri yaninda osteoporoz da gorulebilmekte-dir. Amacimiz talasemi major tanisi olan hastalarda osteoporoz sikligini degerlendirmektir. Yontem: Calismaya talasemi major tanisi alip takipte olan bireyler dahil edildi. Kemik mineral dansitesi T ve Z skorunun -2.5'in altinda olmasi osteoporoz, -1 ile -2.5 arasinda olmasi ise osteopeni olarak kabul edildi. Hastalarin osteoporoz agisindan tedavi alip almadiklari sorgulandi. Bulgular: Calismaya 14'u erkek, kadin toplam 25 talasemi major hastasi alindi. Hastalarin yas ortalamasi 22.0±0.90 yildi. Kemik mineral dansitesi skorlarina gore hastalarin 16'sinda hem Z hem de T skorlarina gore osteoporoz, 9 hastada ise osteopeni saptandi. Bu hastalarin higbirisine daha once osteoporoz taramasi yapilmamis ve herhangi bir destek tedavisi de baslanmamisti. Sonuc: Talasemi major hastalarinin kalan hayatlarini ve yasam ka-litesine olan etkileri agisindan kemik dansitometri ile taranmasinin ve uygun tedavilere en erken donemde baslanmasinin onemli ol-dugu gorusundeyiz.
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