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A rare case report of Dowling- Degos disease: Reticulate acropigmentation of kitamura overlap

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2015

Key Words:

Author Name
Abstract (2. Language): 
Dowling Degos disease (DDD) and Reticulate Acropigmentation of Kitamura (RAPK) belong to a rare group of autosomal dominant inherited reticulated pigmentary disorders. We are reporting a case of a 38 year old female patient who presented to us with multiple asymptomatic dark coloured lesions over the dorsa of the hands and feet, axilla, groin, periorbital region, front and sides of neck. There were also multiple dark comedo-like lesions, perioral pitted acneiform scars and multiple palmar pits. Based on the clinical and histopathological findings, a diagnosis of an overlap of DDD and RAPK was made. Such overlaps of features of reticulate pigmentation have been rarely mentioned in the literature.
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REFERENCES

References: 

1. Cabral AR, Santiago F, Reis JP. Coexistence of reticulate acropigmentation of Kitamura and Dowling-
Degos disease. Dermatol Reports 2011; 3(2):e33. doi: 10.4081/dr.2011.e33.
2. Kim YC, Davis MD, Schanbacher CF, Su WP. Dowling- Degos disease (reticulate pigmented anomaly of
the flexures): a clinical and histopathologic study of 6 cases. J Am AcadDermatol1999;40:462-467.
3. Tang JC, Escandon J, Shiman M, Berman B. Presentation of Reticulate Acropigmentation of Kitamura and
Dowling- Degos Disease Overlap. J ClinAesthetDermatol 2012;5(5):41-43.
4. Vasudevan B, Verma R, Badwal S, Pragasam V, Moorchung N, Badad A. A case of reticulate
acropigmentation of Kitamura: Dowling Degos disease overlap with unusual clinical manifestations. Indian
J Dermatol 2014;59:290-292.
5. Betz RC, Planko L, Eigelshoven S, Hanneken S, Pasternack SM, Bussow H, et al. Loss-of-function
mutations in the keratin 5 gene lead to Dowling- Degos disease. Am J Hum Genet 2006;78:510-519.
6. Li CR, Xing QH, Li M, Qin W, Yue XZ, Zhang XJ, et al. A gene locus responsible for reticulate pigmented
anomaly of flexures maps to chromosome 17p13.3. J Invest Dermatol 2006;126:1297-1301.
7. Schmeider A, Pasternack SM, Krahl D, Betz RC, Leverkus M. Galli- Galli disease is an acantholytic
variant of Dowling- Degos disease: Additional genetic evidence in a German family. J Am AcadDermatol
2012;66:250-1.
8. Sharma R, Sharma SC, Radotra BD, Kaur S. Reticulate acropigmentation of Kitamura. ClinExpDermatol
1989;14(4):302-3.
9. Kovarik CL, Spielvogel RL, Kantor GR. Pigmentary Disorders of the Skin. In: Elder DE, Elenitsas R,
Johnson BL, Murphy GF, Xu X, editors. Lever’s histopathology of the skin. 10th ed.
Philadelphia:Lippincott Williams and Wilkins; 2009. p.689-697.
10. Wenzel J, Tappe K, Gerdsen R, Uerlich M, Phillip-Dormstonw, Bieber T, et al. Successful treatment of
Dowling- Degos disease with Er:YAG laser. DermatolSurg2002;28:748-758.

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