Buradasınız

Anasayfa » Content

Anaesthetic considerations for patient of Hereditary Spherocytosis for splenectomy and cholecystectomy: A case report

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2014

Key Words:

Author Name
Abstract (2. Language): 
Hereditary spherocytosis (HS) is an inherited haemolytic disorder characterised by anaemia, jaundice and splenomegaly. The primary lesion is reduced deformability of erythrocytes which are trapped and destroyed in the spleen resulting in haemolysis and anaemia. Common complications include cholelithiasis, haemolytic episodes, and aplastic crisis. Splenectomyis curative. Here we report the case of a 19-year old female HS patient who underwent splenectomy and cholecystectomy under general anaesthesia.The chief considerations in perioperative management include pre-emptive erythrocyte transfusion, proper hydration and avoidance of hypoxia, hypercarbia and acidosis.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastirmax-anaesthetic-considerations-patient-hereditary-spherocytosis-splenectomy-and-cholecystectomy-case-report.pdf
  • 1
295
297
  • English

REFERENCES

References: 

1. Bolton-Maggs PH, Stevens RF, Dodd NJ, Lamont G, Tittensor P, King MJ, et al. Guidelines for the
diagnosis and management of hereditary spherocytosis. Br J Haematol 2004;126:455-74.
2. Agre P, Asimos A, Casella JF, McMilan C: Inheritance pattern and clinical response to splenectomy as
a reflection of erythrocyte spectrin deficiency in hereditary spherocytosis. N Eng J Med 1986 Dec 18;
315 (25): 1579-83.
3. Steinberg MH. Management of sickle cell disease N Eng J. Med 1999; 340: 1021-30.
4. Shapiro ND, PoeMF. Sickle cell disease, an anaesthesiological problem, Anaesthesiology 1995; 16:
771-80.
5. Hassan A, Babadoko AA, Isa AH, Abunimye P. Hereditary Spherocytosis in a 27-year old female: case
report. Annals of African Medicine vol 8, No1;2009:61-63 .
6. Mariani M, Barcellini W, Vercellati C, Marcello AP, Fermo E, Pedotti P, et al. Clinical and
hematologic features of 300 patients affected by hereditary spherocytosis grouped according to the type
of the membrane protein defect. Haematologica 2008;93:1310-7.

Thank you for copying data from http://www.arastirmax.com