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Mathematical Analysis of the Global Dynamics of an SVEIR Epidemic Model with Herd Immunity

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Abstract (2. Language): 
The SVEIR epidemiological model was presented to gain insight into the mathematical epidemiological model with herd immunity in the population. Positivity of solution was shown for the mathematical and epidemiological well posed of the model. The stability of the model was analyzed for the existence of disease free and endemic equilibrium points. The threshold quantity “Basic Reproduction Number” ( 0 R ) with and without vaccine was derived using next generation matrix method (NGM), and it is shown that the disease free equilibrium point is locally asymptotically stable whenever the basic reproduction number is less than unity i.e. ( R0 1 ), otherwise endemic whenever it exceeds unity ( 0 R 1). Global stability of endemic equilibrium was analyzed using Lyapunov method and numerical simulation of the model was carried out using Runge-Kutta method of order four (4) with MAPLE 18. Results showed that herd immunity can only be attained whenever everyone in the population is vaccinated against the infection, since ( Vaccine 0 R R ).
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REFERENCES

References: 

[1] Anderson RM, May RM. Directly transmitted infectious diseases; control by vaccination. Science 1982;215:1053-60.
[2] Andrew W. 2016: Notes on Herd Immunity from Andrew Wakefield-Vaxxed
[3] CDC. Impact of vaccines universally recommended for children—United States, 1900–1998. MMWR 1999; 48:243–8.
[4] CDC. National, state, and urban area vaccination coverage levels among children aged 19–35 months—United States, 2000. MMWR 2001;50: 637–41.
[5] CDC. Recommended childhood immunization schedule—United States, 2001. MMWR 2001;50 :7–10, 19.
[6] CDC. Ten great public health achievements—United States, 1900–1999. MMWR 1999;48: 241–243.
[7] Cvjetanovic B, Grab B, Dixon H. Epidemio- logical models of poliomyelitis and measles and their application in the planning of immuniza- tion programmes. Bull World Health Organ 1982;60:405-22.
[8] Dorland's illustrated medical dictionary. 24th ed. Philadelphia, PA: WB Saunders, 1965.
[9] Driessche P. and Watmough J., Basic Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission, Mathematical Biosciences 180, Pp 29–48. (2002) .
[10] Dubos R, Dubos J. The white plague: tubercu- losis, man, and society. New Brunswick, NJ: Rutgers University Press, 1952. (16)
[11] Editorial Team of Vaccine Today, (2015);
[12] “What is herd Immunity?: vaccine today European Journal of Epidemiology, vol.16, no.7.pp 601-606.
[13] Freed GL, Katz SL, Clark SJ. Safety of vaccinations: JAMA 1996;276:1869–72. (8).
[14] http:/vaxxedthemovie.com/note-herd-immunity-andrew-wakefield download on 7th July.
[15] https://WWW.vaccinestoday.eu/sorie/what-is-herd-immunity
[16] John, T.J and Samuel, R. (2000); “Herd Immunity and herd effect; new insights and definition”
[17] Last JM. A dictionary of epidemiology. 2nd ed. New York, NY: Oxford University Press, 1988.
[18] Meissner H.C, (2015); “Why is herd immunity so Important?” Journal of America Academy of Pediatrics. 36/5/14.1
[19] Section 317 of the Public Health Service Act, 42 U.S.C. 247b.
[20] Topley WWC, Wilson GS. The spread of bacterial infection. The problem of herd immunity. J Hyg 1923;21:243-9.

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