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Ondokuz Hafta Gebelikte Misoprostol Kullanımına Bağlı Uterus Rüptürü

Uterine Rupture with Misoprostol at 19 Week of Gestation

Journal Name:

Publication Year:

DOI: 
10.5505/abantmedj.2017.24865

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: Misoprostol is a synthetic prostaglandin E1 analogue that has been used commonly at obstetric practice even though received approval as an oral agent for the preventing of gastric ulcers. Its’ widely used at obstetric practice such as first and second trimester pregnancy termination, labor induction at term and management of postpartum hemorrhage. Even though its’ efficacy and widespread use, its safety is questioned in women with prior caesarean birth by the reason of increasing number of uterine rupture. Materials and method: We report a second trimester pregnant women with demised fetus with the history of myomectomy and prior low segment caesarean section who had uterine rupture after misoprostol administration. Results: Because of uterine rupture, we performed emergency laparotomy and repaired the rupture line Conclusion: Misoprostol has to be used more careful at patients with prior uterine surgery do to the increased uterine rupture risk.
Abstract (Original Language): 
Amaç: Sentetik prostaglandin E1 analoğu olan misoprostol, gastrik ülser tedavisi için onay almış olmasına rağmen kadın hastalıkları ve doğum pratiğinde birinci ve ikinci trimester gebelikleri sonlandırmada, term gebeliklerde doğum indüksiyonunda ve postpartum kanamaların yönetiminde sık olarak kullanılmaktadır. Misoprostolün güvenilirliği, yaygın kullanılması ve tedavide etkin olmasına rağmen geçirilmiş sezaryen öyküsü olan hastalarda artan uterus rüptürü nedeniyle sorgulanmaktadır. Materyal ve Metod: Olgu sunumunda, ölü fetus tanısı ile gebelik terninasyonu planlanan 19 haftalık gebeliği bulunan, geçirilmiş alt segment sezaryen ve myomektomi öyküsü olan hastada misoprostol kullanımı sonrası ortaya çıkan uterus rüptürünü sunacağız. Bulgular: Misoprostol kullanımı sonrası hastada uterus rüptürü meydana gelmiş, hasta acil olarak ameliyata alınıp kanama durdurulmuş ve rüptür hattı onarılmıştır Sonuç: Geçirilmiş uterus cerrahisi öyküsü olan gebelerde misoprostol kullanımı ile uterus rüptürü riski artmakta olup Misoprostol, daha dikkatli kullanılmalıdır.
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REFERENCES

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