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1999-2000 yıllarında Selçuk Üniversitesi Tıp Fakültesi Hastanesinde izole edilen Salmonella ve Shigella türlerinin çeşitli antimikrobîklere duyarlılıkları*

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Abstract (2. Language): 
in this study the in vitro activities of twelve antimicrobial agents against 50 Salmonella and 25 Shigella strains isolated in the years 1999 and 2000 at the Microbiology Laboratory of the University of Selçuk Faculty of Medicine were investigated by E test method. Of the 50 Salmonella strains 30 were identified as S. thyphimurium and 20 as S.enteritidis. İn this study for Salmonella isolates resistance to ampiciliin was most common (90%), follovved by tetracycline (64%), chloramphenicol (48%), trimethoprim/sulfamethoxazole (16%), cefuroxime (16%), cefodizime, ceftrİaxone, ceftazidime and cefepime (6%). AH isolates were susceptible to meropenem, imipenem and ciprofloxacin. For 25 shigella isolates of our study the resistance were 88% for ampiciliin, 76% for tetracycline, 64% for trimethoprim/suiphamethoxazole, 28% for chloramphenicol, 12% for cefuroxime and 4% for ciprofioxacin. AH Shigella İsolates were sensitive against meropenem, imipenem, cefodizime, ceftriaxone, ceftazidime and cefepime.
Abstract (Original Language): 
Bu çalışmada 1999-2000 yıllarında Selçuk Üniversitesi Tıp Fakültesi Hastanesi Merkez Mikrobiyoloji Laboratuvan'nda izole edilen 50 Salmonella, 25 Shigella suşunun 12 antimikrobiğe gösterdikleri direnç E test yöntemi ile araştırıldı. İzole edilen 50 Salmonella suşunun serotiplendirmesinde 30'unun (%60) S.thyphimurium, 20'sinin (%40) S.enteritidis olduğu saptandı. İzole edilen 25 Shigella suşunun tamamının S.sonnei olduğu belirlendi. Salmonella suşlarında en yüksek direnç ampisilin'e (%90) karşı gözlendi, bunu tetrasiklin (%64), kloramfenikol (%48), trimetoprim/sulfametoksazol (%16), sefuroksim (%16), sefodizim, seftriakson, seftazidim, sefepim (%6) direnci İzledi. Tüm Salmonella suşları meropenem, imipemen ve siprofloksasine duyarlı bulundu. 25 Shigella suşu ampisiline %88, tetrasikline %76, trimetoprim-sulfametoksazole %64, kloramfenikole %28, sefuroksime %12, siprofloksasine %4 dirençli bulundu. Tüm Shigella izolatlarının meropenem, imipenem, sefodizim, seftriakson, seftazidim ve sefepime duyarlı olduğu saptandı.
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REFERENCES

References: 

1. Goodman L, Segreti J. Infectious diarrhoea. Dis Mon 1999;45:268-99.
2. Mims CA, Playfair JH, Roit İM, Wakelin D, Williams R, Anderson RM: Medical Microbioiogy, Mosby Year Book Europe Limited: Hong Kong;1993:p. 25.1-25.30.
3. Brooks GF, Butel JS, Ornston LN, Jawetz E, Melnick JL, Adelberg EA: Medical Microbioiogy, Appleton & Lange: USA;1995:p. 206-17.
4. Tassios PT, Markogiannakis A, Vatapouloa AC, Kat-sanikou E, Velonakis EN, Kourea-Kremastinou J, Le-gakis NJ. Molecular epidemiology of antibiotic re-sistance of Salmonella enteritidis during a 7 year period in Greece. J Clin Microbiol 1997;35:1321-7.
5. National Committee for Clinical Laboratory Standards. Performance Standards for antimicrobial disk sus-ceptibility testing. 8th Informational Supplement NCCLS Documents M100-S8. Pennsylvania: USA; 1998.
6. Narkeviciute O, Braskuviene V, Zilenaite V, Ba-likynaite V, Segejeva L. Current antimicrobial re¬sistance of Shigella, Salmonella in Vilnus University Children's hospital. 9th European Congress of Clinical Microbioiogy and Infectious Diseases Kongre Kitabı; 1999;Berlin, Almanya, p.236.
7. Orellana MA, Aramendi M, Galera G, Moyano C, Amerigo MA. Antibiotic resistance evolution of enteric Salmonella and susceptibility pattern. 9th European Congress of Clinical Microbioiogy and Infectious Di-seases Kongre Kitabı; 1999;Berlin, Almanya, p. 239.
8. Hakanen A, Siitonen A, Kotîlainen P, Huovinen P. Inc-resing fluoroquinolone resistance and multiresistance in Salmonella isolates of foreign origin in Finland pat¬tern. 9th European Congress of Clinical Microbioiogy and Infectious Diseases Kongre Kitabı; 1999;Berlin, Almanya, p. 302.

9. Threlfall EJ, Ward LR, Rowe B. Resistance to cip-rofloxacin in non-typhoidal Salmonellas from humans in England and Wales-the current situation. Clin Mic Infect 1999;5:130-4.
10. Erdem B. 1995-1997 Yıllarında serotiplendirilen Sal-monella'lar. Infeksiyon Derg 1998;12:313-16.
11. Çırak MY, Yakıncı G, Rota S, Sultan N. Gazi Üniversitesi Tıp Fakültesi'nde 1995-1997 yılları arasında saptanan Salmonella prevelansı ve an-tibiyotik direnci. İnfeksiyon Derg 1999;13:351-4.
12. VVillke A, Arman D, Çokça F, Sümerkan B, Söyletir G, Bakır B, Sırmatel F, Leblebicioğlu H, Kılıç S. Re-sistance of Salmonella and Shigella in Turkey. Clin Microbiol Infect 1999;5:588-90,.
13. Akan O, Kanra G, Secmeer G, Ceyhan M, Ecevit Z. Berkman E. Antibiotic susceptibilities of Salmonella serogroups isolated from Turkish Children. Turk J Pe-diair 1997;39:7-11,.
14. Tuncer İ, Baysal B, Günaydın M, Saniç A, Baykan B. Dışkı örneklerinden izole edilen Salmonella thyphi-murium suşlarmın çeşitli antimikrobiklere direnci: ANKEM Derg 1990;4:537-40.
15. Yıldırmak T, Yazgan A, Özcengiz G. Multipie drug re-sistance patterns and plasmid profiles of non-typhi Salmonella in Turkey. Epidemiol Infect 1998;121:3303-7,.
16. Aleksic S, Katz A, Aleksic V, Bockemuhl J. Antibiotic resistance of Shigella strains isolated in the Federal Republic of Germany 1989-1990. İnt J Med Microbiol Virol Parasitol Infect Dis 1993;279:484-93,.
17. Guyot A. Antibiotic resistance of Shigella in Monrovia. Trop Doct 1996;26:70-1.
18. Aysev AD, Guriz H. Drug resistance Shigella strains isolated in Ankara, Turkey 1993-1996. Scand J Infect Dis 1998;30:351-3,.

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