Relation of high resolution computed tomography findings with functionnal
Keywords (Original Language):
| Author Name | University of Author | Faculty of Author |
|---|---|---|
Abstract (2. Language):
Objectives: We investigated in stable asthma and chronic obstructive pulmonary disease (COPD) cases, the comparison of HRCT scan
abnormalities with the correlation of biometric and functional parameters.
Methods: 29 nonsmoker asthma patients; average age 46.7 ± 14.6, and 20 smoker/ex-smoker COPD patients; average age 65.4 ± 10 were
studied. The patients were stable during last three weeks and agreed to have HRCT and respiratory function tests.
Results: There were no significant differences in the mean FVC and FEV1 parameters between two groups (p=0.498, p=0.198). But, FEV1/FVC
and FEF25-75 decreased in COPD group (p<0.0001, p=0.016).
27.5%of asthma and 20% of COPD patients had normal HRCT findings during evaluation. 41,4%of asthma and 30% of COPD patients
showed bronchial wall thickness. 27.6% of asthma and 40% of COPD patients had tubular bronchiectasis. 20.7% of asthma and 5% of
COPD patients had air-trapping bronchiectasis. All those findings were not significant with X2 test, between two groups. Only statistically
significant result was 13.8% of asthma and 60% of COPD patients had emphysema (p<0.001).
Conclusion: We conclude that the statistical significance found for emphysema parameter is not important for the differentiation of two
groups, as either asthma or COPD patients present similar remodeling patterns on HRCT scans.
Bookmark/Search this post with
FULL TEXT (PDF):
- 1