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BIOCERAMIC AS DRUG DELIVERY SYSTEM IN ORTHOPEDIC GRAFT

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Abstract (2. Language): 
Ceramic substances are in the market as bone substitutes, which include calcium phosphate ceramics like Tricalcium phosphate (TCP) and Hydroxyapatite (HAp). Calcium phosphate based bioceramics have been used in medicine and dentistry for nearly 30 years. Applications include dental implants, percutaneous devices and joint replacements. Different phases of calcium phosphate ceramics are used depending weather a resorbable or bioactive material is required. The material used for this study was a Calcium phosphate (Biphasic) granule, consisting of different ratios of relatively stable Hydroxyapatite and more soluble Tricalcium phosphate phases, thereby controlling the resorbability of the bioceramic for drug release. The drug used for encapsulation and subsequent release is Teriparatide
105-108

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