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EFFECT OF ALOE VERA (L). BURM. F POLYSACCHARIDE ON VARIOUS IMMUNE PARAMETERS

Journal Name:

  • Advance Research in Pharmaceuticals and Biologicals

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
In present study, we studied the effect of Aloe vera polysaccharide on various immune parameters. Aloe Vera polysaccharide showed significant (p<0.001) stimulation of phagocytosis (82.9924+2.4488) at a concentration 100 μM. Aloe vera polysaccharide at 200 μM had no significant cytotoxic effect towards human lymphocytes. The polysaccharide was examined for its antioxidant potential. Aloe polysaccharide possesses observable antioxidant activity as its EC50 value was found to be 3.5μgm/ml, which is significant when compared to standard solution of ascorbic acid whose EC50 value is 2.86μm/ml. Aloe vera inner gel was evaluated for its antimicrobial activity against Escherichia coli. In the present study, the inner gel of Aloe vera was tested for its antibacterial property against Escherichia coli (strain no: NCIM 2118) using pour plate method. The fresh gel at 50%-100% showed significant inhibition of growth of the colonies. These results indicate that Aloe Vera polysaccharide possess significant immunomodulatory activity and other therapeutic uses such as an antioxidant
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  • 3
300-304
  • English

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