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Evaluation of Wound Healing Activity of Leaves of Bambusa arundinace

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Abstract (2. Language): 
For thousands of years, medicinal plants have played an important role throughout the world in treating and preventing a variety of diseases and still now, the preference of herbal drugs is ever increasing. Tribal people still depend on medicinal plants and most of them have a general knowledge of medicinal plants which are used as first aid remedies to treat cough, cold, fever, headache, poisonous bites and some simple ailments. Selected medicinal plant Bambusa arundinacea is used traditionally in hyperlipidemia, rheumatism, arthritis, obesity, inflammation, wrinkles etc. The present review explores relevant information about the screening of leaves obtained from Bambusa arundinacea in its wound healing potential as per the basis of its antiinflammatory, antibacterial and antioxidant properties. In the present study, the ethanolic extract of leaves of Bambusa arundinacea showed significant wound healing activity in the excision and incision wound models in rats. The progression of wound healing (area reduction) is 86.60% by 10% ethanolic extract at day 12th. The results of the 12th day indicate that there is significant increase in the hydroxyproline content in extract groups, in incision wound model as compared to the group treated with standard drug i.e. povidone iodine.
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REFERENCES

References: 

1. J. A. McGrath, R. A. J. Eady, and F. M. Pop. Textbook
of Anatomy and organisation of skin, Peelhike
publications, 6th edition, 2008, pp. 67-69.
2. Wikipedia, 2011, The free Encyclopedia: Wounds in
humans and animals.
3. M. Munniappan and T. Sundararaj. Antiinflammatory
and antiulcer activity of Bambusa
arundinacea, Journal of ethnopharmacology, 88:
161-167 (2002).
4. P.W. Wertz. Lipids and barrier function of the skin,
Acta Derm Venereol; Supplement, 208: 7-11 (2000).
5. C. M. Kathi. Barrier Function of the Skin: "La Raison
d'Être" of the Epidermis Journal of Investigative
Dermatology, 121: 231–241 (2003).
6. I. H. Blank, R. J. Scheuplein. Transport into and
within the skin, British Journal of Dermatology; 81:
4-10 (1969).
7. M. L. Williams, P. M. Elias. The extracellular matrix
of stratum corneum- Role of lipids in normal and
pathological function, Critical Review of
Therapeutic Drug Carrier System 3: 95-122 (1987).
Abhinav et al., ARPB, 2013; Vol 3 (I) ISSN 2250-0774
(RESEARCH ARTICLE)
383 | P a g e w w w . a r p b . i n f o
8. R. E. Bellingham, P. D. Medawar. Contracture and
septive growth in the Healing of extensive wounds
in mammalian skin, Journal of dermatology 5: 233-
235 (1950).
9. K. Hunt Thomas, H. Hopf, Z. Hussain. In Advance in
skin and wound care physiology of wound healing,
345 (2000).
10. Shattuk & H. Hartwell. The mechanism of healing of
wounds in human and animals, Springfeild
publications, 7th edition, 2010, pp. 145-156.
11. M. Singh, R. Govindarajan, V. Nath, A. Rawat and S.
Mehrotra. Antimicrobial, wound healing and
antioxidant activity of Plagiochasma
appendiculatum Lehm. et Lind, Journal of
Ethnopharmacology 107 (01):67-72 (2006).
12. E. H. Park and M. J. Chun. Wound healing activity of
Opuntia ficus-indica, Fitoterapia 72 (02): 165-167
(2001).
13. A. D. B. Vaidya. Reverse pharmacological correlates
of ayurvedic drug action, Indian Journal of
Pharmacology 38 (05): 311-315 (2006).
14. A. N. Rao, H. Keng and Y. C. Yee. Problems in
conservation of plant resources in South East Asia,
Journal of Ethnopharmacology 3 (02): 144-146
(1983).
15. H. Mohan. Textbook of pathology, Jaypee Brother
Medical Publishers (P) Ltd, New Delhi, 2005, pp.
133-175.
16. S. K. Purna, M. Babu. Traditional medicine and
practices in burn care: need for newer scientific
perspectives, Burns 24: 387-388 (1998).
17. Robbins and Cortran. Pathologic basis of disease,
Elsevier Publication, 7th Edition, 2004, pp. 47-87.
18. K. Inkinen, R. Turakainen, H. Wolff, L. Ravanti, V. M.
Kahari, J. Ahonen. Expression and activity of matrix
metalloproteinase-2 and -9 in experimental
granulation tissue, APMIS 108 (5): 318-328 (2000).
19. J. C. Maruzzcalla, P. A. Henry. The antimicrobial
action of perfume oils, Journal of American
Pharmaceutical Association 28 (7): 471-475
(1958).
20. E. Mokaddas, V. O. Rotimi and S. C. Sanyal. In vitro
activity of piperacillin/tazobactam versus other
broad antibiotics against nosocomial gram negative
pathogens isolated from burn patients, Journal of
Chemotherapy 10 (3): 208-214 (1998).
21. A. N. Neely, R. L. Brown, C. E. Clendening, M. M.
Orloff, J. Gardner and D. G. Greenhalgh. Proteolytic
activity in human burn wounds, Wound Repair and
Regeneration 5: 302-309 (1997).

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