Buradasınız

FAST DISSOLVING TABLETS∶ METHOD AND TECHNOLOGY REVIEW

Journal Name:

Publication Year:

Abstract (2. Language): 
In the recent years, many of the pharmaceutical groups are focusing their research work on fast dissolving tablets. Fast dissolving tablets are an innovative drug delivery system in which the consumption of the dosage form without any use of water in taking. So, now-a-days, most of the pharmaceutical companies adopted various technologies to manufacture fast dissolving oral formulation in large scale despite of several limitations as an alternative to traditional over-thecounter medicine forms such as tablets, capsules etc. The main advantage of this technology is the administration to paediatrics and geriatrics patient population where the difficulty of swallowing larger oral dosage forms is eliminated. The basic approach used in development of FDT is the use of superdisintegrants like Cross linked carboxymelhylcellulose (croscarmellose), primogel, polyvinylpyrrolidone (polyplasdone) etc or maximizing pore structure in the formulation. The review describes the various methods and technologies employed in this research area.
487
498