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IN-VITRO EVALUATION OF ANTIOXIDANT POTENTIAL OF ROOT OF AERVA JAVANICA

Journal Name:

  • Advance Research in Pharmaceuticals and Biologicals

Publication Year:

  • 2014

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Author Name
Abstract (2. Language): 
Aerva Javanica belonging to family (Amaranthaceae) is used as Pasanabheda means one, which breaks the kidney stone and therefore, in Gujarati it is commonly known as Patharphod. It is used in traditional medicine as it has been claimed to be useful in treating rheumatism, swelling, toothache, inflammation, headache and kidney problems. A detailed review of literature afforded no information on the in-vitro antioxidant potential of the same plant. It was therefore worthwhile to investigate free radicals scavenging effect of Aerva Javanica. The main objective of this study was to evaluate the free radical scavenging potential of the A. Javanica by using different antioxidant models of screening. Invitro antioxidant activity of A. javanica was performed by using alcoholic and aqueous extract. Both the extract of root of A. Javanica was determined by ABTS radical cation decolorization assay, scavenging of DPPH free radical, reduction of ferric ions, inhibition of lipid peroxide formation and total antioxidant activity as per standard methodology. For the present study, ascorbic acid was used as reference standard and positive control. Based on our findings, the alcoholic extract of root of Aerva Javanica showed very potent free radical scavenging activity. Therefore, it was concluded that alcoholic extract of root of Aerva javanica showed potent in-vitro antioxidant activity.
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