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KOMŞU ORGANLARA DOĞRUDAN YAYILMA GÖSTEREN MİDE KARSİNOMU OLGULARINDA REZEKTİF CERRAHİ GİRİŞİMİN SONUÇLARI

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Abstract (2. Language): 
274 patients with gastric carcinoma had undergone resection between 1989 and 1993. Of 274 patients, 87 (34%) had cancer extending to adjacent organs. In this study, the late results of resective procedures in 87 patients with gastric carcinoma extending to adjacent organs is reported. These 87 patients were classified into two groups: Group I included 38 patients without peritoneal dissemination, liver metastasis and widespread nodal involvement. Group II consisted of 49 patients with positive evidence of incurability. Results.- Among group I patients, gastrectomy, complete removal of invaded organs and sufficient lymphadenectomy were performed in 74 patients. In these patients, 5 year survival rate was 31.7%. Remaining 14 patients were treated with gastrectomy alone or with incomplete removal of invaded organs. In these patients, 5-year survival rate was 4.1 % and significantly lower than that of 24 patients. In group II there were 49 patients with incurable factors and 5-year survival rates were 3.4 and 0% in complete (16) and incomplete (33) excisions, respectively. Conclusion.- Gastrectomy, complete removal of invaded organs and sufficient lymphadenectomy should be performed in patients with gastric carcinoma extending to adjacent organs and without positive evidences of incurability. This aggressive surgical treatment (en blac resection) provides higher 5-year survival rates than those of incomplete resection. Involvement of one adjacent organ, treated with complete excision, was a sign of a better outcome compared to involvement of multiple adjacent organs.
Abstract (Original Language): 
1989-1993 yıllan arasında 274 mide karsinomu hastasına rezeksiyon yapıldı. Rezeksiyon yapılan 274 hastadan 87 (%34)'sinde kanser, komşu organlara doğrudan yayılmıştı. Biz, rezeksiyon yapılan 87 hastadaki geç sonuçları irdeledik. Hastalar iki gruba ayrılmıştır. Grup I'e, yaygın periton metastazı, karaciğer metastazı, yaygın nodül tutulması olmayan 38 hasta dahil edilmiştir. Grup II ise, bu inkürabl faktörleri taşıyan 49 hastadan ibarettir. Grup I'de yer alan 24 hastaya, gastrektomi, invazyonlu organların tam çıkarılması ve yeterli lenfadenektomi uygulanmıştır. Bu 24 hastada 5 yıllık sürvi oranı % 31, 7 idi. Kalan 14'ünde, ya tek başına gastrektomi uygulanmış veya gastrektomi ile birlikte komşu invazyonlu organlarda kısmi rezeksiyon uygulanmıştır. Bu 14 hastada, 5 yıllık sürvi oranı %4.1 bulunmuştur. Grup II'de inkürabl faktörler olan 49 hasta mevcuttu. 5 yıllık sürvi oranları tam eksizyon yapılan 16 olguda %3.4 tam eksizyon yapılamayan 33 olguda ise %0'dır. Komşu organlarda invazyon meydana getirmiş ancak inkürabilite bulguları olmayan mide karsinomlu hastalarda gastrektomi, invazyona uğramış organların bütünüyle çıkarılması ve yeterli lenfadenektomi uygulanmalıdır. Bu agressif cerrahi tedavi (en bloc rezeksiyon) inkomplet rezeksiyona göre daha yüksek bir 5 yıllık sürvi sağlar. Komşu organ invazyonu olan ve inkürabilite bulgulan olan hastalarda ise, eğer komşu organ tutulmuşsa, komplet eksizyon ile, iyi sonuçlar elde edilebilir. Fakat komşu organ tutulması varsa, komplet ve inkomplet eksizyon sonuçlarında farklar yoktur.
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