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UREAPLAZMA UREALYTICUM VE CHLAMYDIA TRACHOMATIS ENFEKSİYONLARININ SEMEN PARAMETRELERİNE ETKİSİ

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Abstract (2. Language): 
Aim of this study is to determine the effect of urogenital Ureaplasma urealyticum and Chlamydia trachomatis infections to the semen parameters. 47 randomly chosen infertile and 22 fertile men were enrolled in this study. Semen were analysed according to WHO 1992 and morphology according to Kruger's strict criteria. Each semen specimen was tested for sperm autoantibobies, semen culture were done and specimens were tested for chlamydia trachomatis and ureaplasma urealyticum. The women in infertile couples were investigated by hormon profiles, histerosalphingographies and basal body temperatures. Results.- C. trachomatis and/ or U. urealyticum were positive in 57.5% of infertile patients while these were positive in 27% of fertile patients. There was no significant difference in sperm count and morphology while the decrease of sperm motility was significant. (p=0.0076 and 0.0114 respectively). The antisperm antibody count was positive in 36.4% of patients with positive Chlamydia and Ureaplasma infection and it was positive in 14% of patients with negative Chlamydia and Ureaplasma infection. Conclusion.- C. trachomatis and U. urealyticum are two microorganisms which may have a role in infertility.
Abstract (Original Language): 
Ürogenital sistemde Ureaplazma urealyticum ve Chlamydia trachomatis enfeksiyonlarının semen parametrelerine etkisini araştırmayı amaçlayan bu çalışmaya randomize seçilen 47 infertil ve 22 fertil erkek alındı. Semen analizleri WHO 1992 ve morfolojileri Kruger kriterlerine göre değerlendirildi: Her semen örneğinde sperm antikoru bakıldı, semen kültürü yapıldı, Chlamydia trachomatis ve Ureaplazma urealyticum mevcudiyeti araştırıldı. İnfertil çiftlerde kadınlar bazal ısı tayinleri, histerosalphingografi ve hormon profilleri ile incelendiler. İnfertil grupta %57.5 oranında C. trachomatis ve/veya U. urealyticum saptanırken fertil grupta %27 olarak saptandı. Chlamydia ve Ureaplazma enfeksiyonu olan hastalarda sperm sayı ve morfolojisi bakımdan anlamlı fark yokken, sperm motilitesi anlamlı biçimde azalmıştı (sırasıyla p=0.0076 ve 0.0114). Antisperm antikor pozitifliği Chlamydia ve Ureaplazma enfeksiyonu olanlarda %36.4, olmayanlarda %14 oranında bulundu. Sonuç olarak C. trachomatis ve U. urealyticum'un sperm motilitesini bozabilen ve infertilitede rolü olabilecek iki patojen olduğu görülmektedir.
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