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Mide Yerleşimli Bir Gastrointestinal Stromal Tümörün Laparoskopik Rezeksiyonu

Laparoscopic resection of a gastrointestinal stromal tumour located in stomach

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Abstract (2. Language): 
Gastrointestinal tumors (GISTs) represent the largest category of nonepithelial neoplasms of the gastrointestinal tract. They arise from the neoplastic degeneration of primitive mesenchymal cells and demonstrate considerable variability in their differentiation pathways. GISTs can occur in all segments of the intestine mostly occuring in the stomach and small intestine. The clinical course of GISTs is heterogeneous and the most important prognostic factors are tumor size, mitotic count, and the presence of c-kit gene mutation. Here we report a case with a huge GIST, finally resected laparoscopically, which presented with melena and a polypoid mass measuring 3cmx3cm during upper gastrointestinal endoscopy.
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REFERENCES

References: 

1. Miettinen M, Majidi M, Lasota J. Pathology and diagnostic
criteria of gastrointestinal stromal tumors: a
review. Eur J Cancer 2002; 38: 39-51.
2. Dizdar Ö, Güler N. Gastrointestinal stromal tümörler
ve imatinib tedavisi. Hacettepe Tıp Dergisi 2004; 35:
87-91.
3. Sturgeon C, Chejfec G, Espat N. Gastrointestinal stromal
tumors: a spectrum of diseases. Surg Oncol 2003;
12: 21-26.
Cerrahpafla Tıp Derg 2008; 39(1): 33-36
4. Pidhorecky I, Cheney RT, Kraybill WG, Gibbs JF.
Gastrointestinal stromal tumors: Current diagnosis,
biologic behavior, and management. Ann Surg Oncol
2000; 7: 705-712.
5. Meester B, Pauwels PA, Dijnentcog AM, et al.
Metastasis in a benign duodenal stromal tumour. Eur
J Surg Oncol 1998; 24: 334-335.
6. Goh BK, Chow PK, Ong HS, Wong WK.
Gastrointestinal stromal tumor involving the second
and third portion of the duodenum: Treatment by partial
duodenectomy and Roux-en-Y duodenojejunostomy.
J Surg Oncol 2005; 4: 273-275.
7. Jeon SW, Park YD, Chung YJ, et al. Gastrointestinal
stromal tumors of the stomach: Endosonographic differentiation
in relation to histological risk. J
Gastroenterol Hepatol 2007; 22: 2069-2075.
8. Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of
gastrointestinal stromal tumors: a consensus
approach. Hum Pathol 2002; 33: 459-645.
9. Gunawan B, Bergmann F, Hoer J, et al. Biological and
clinical significance of cytogenetic abnormalities in
low-risk and high-risk gastrointestinal stromal tumors.
Hum Pathol 2002; 33: 316-321.
10. Miettinen M, El Rifai W, HL Sobin L, et al. Evaluation
of malignancy and prognosis of gastrointestinal
tumors: a review. Hum Pathol 2002; 338: 478-483.
11. Perek S, Perek A, fiarman K, et al. Duedonal stromal
tümör. Cerrahpafla Tıp Dergisi 2007; 38: 102-105.
12. Fujimoto Y, Nakanishi Y, Yoshimura K, Shimoda T.
Clinicopathologic study of primary malignant gastrointestinal
stromal tumor of the stomach with special
reference to prognostic factors: analysis of results
in 140 surgically resected patients. Gastric Cancer
2003; 6: 39-48.
13. Roberts PJ, Eisenberg B. Clinical presentation of gastrointestinal
stromal tumors and treatment of operable
disease. Eur J Cancer 2002; 38: 37-38.
14. De Matteo RP, Lewis JJ, Leung D. Two hundred gastrointestinal
stromal tumors: recurrence patterns and
prognostic factors for survival. Ann Surg 2000; 231:
51-58.
15. Dematteo RP, Heinrich MC, El-Rifai WM, Demetri G.
Clinical management of gastrointestinal tumors before
and after STI-571. Hum Pathol 2002; 33: 466-477.
16. Joensuu H, Fletcher C, Dimitrijevic S, Silberman S,
Roberts P, Demetri G. Management of malignant gastrointestinal
stromal tumours. Lancet Oncol 2002; 3:
655-664.
17. van Den Abbeele AD, Badawi RD. Use of positron
emission tomography in oncology and its potential
role to assess response to imatinib mesylate therapy in
gastrointestinal stromal tumors. Eur J Cancer 2002;
38: 60-65.

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