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Herpes Ansefalitine Bağlı Kistik Ansefalomalazi: Olgu Sunumu

Herpes Encephalitis Presenting as Cystic Encephalomalacia : A Case Report

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2009

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Herpes simplex virus (HSV) is a common cause of viral encephalitis. Herpes simplex encephalitis (HSE) remains one of the most devastating infections of the central nervous system despite available antiviral therapy. Herpes simplex encephalitis (HSE) typically presents with acute neurological changes and the initial cerebrospinal fluid examination is nearly always abnormal. However, these clinical findings are not pathognomonic because numerous other diseases in the central nervous system can mimic HSE. In the current era, the diagnostic gold standard is the detection of HSV DNA in the cerebrospinal fluid by polymerase chain reaction. Cystic encephalomalacia is uncommon after HSE. In addition it can effect bilateral hemisferic structre and characterised with cystic cavite and gliosis. In this study, it was presented a rare case cystic encephalomalacia occurred after HSV encephalitis.
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Abstract (Original Language): 
Herpes simplek s virüs (HSV), viral ansefalitlerin en sık nedenlerinden biridir. Herpes simpleks ansefaliti (HSE) ise uygun antiviral tedaviye rağmen santral sinir sisteminin en harap edici enfeksiyonu olmaya devam etmektedir. HSE'nin başlangıcında beyin omirilik sıvısı (BOS) sıklıkla anormal ve eşlik eden akut nörolojik bulguların varlığı ise tipiktir. Santral sinir sisteminin birçok hastalığı HSE'e benzer bir tablo oluşturduğundan bu klinik bulgular patognomonik değildir. Günümüzde tanı için altın standart, BOS'da polimeraz zincir reaksiyonu ile HSV DNA'sının tespit edilmesidir. Her iki beyin yarısını etkileyebilen kistik kavite ve gliozisle karakterize yıkıcı bir olay olan kistik ansefalomalazi, HSE sonrası çok nadir görülen bir durumdur. Bu çalışmada, HSV ansefaliti sonrası son derece nadir olarak görülen bir kistik ansefalomalazi olgusu sunulmuştur.
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  • 2
141-144
  • Turkish

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