Buradasınız

Anasayfa » Content

Baş ve Boyun Tümörlerinde Positron Emisyon Tomografi/Bilgisayarlı Tomografi (PET/BT)

Positron Emission Tomography/Computerized Tomography (PET/CT) in Head and Neck Tumors

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Objective: PET/CT is gaining acceptance in staging head and neck tumors in routine practice. Capability of PET/CT to scan whole body, affinity to head and neck tumors and accurate characterization of lymph nodes makes staging easier with PET/CT. In this study, we investigated the importance of PET/CT in staging of head and neck tumors. Materials and Methods: Nineteen patients with head and neck tumors (11 M, 8 F; mean: 50,4±17 years old) were included to the study. PET/CT results of patients were evaluated with follow-up results or histophology as the gold standard. Results: The patients were presented as thyroid carcinoma 3, laryngeal carcinoma 3, etiology of lymphadenopathy 1, lip or palatal tumor 3, mass characterization 3, proximal esophagus carcinoma 2, parotis tumor 3 and facial malign melanoma 1 patient. PET/CT identified residual or recurrent tumor in 4 patients, mass in 9, lymph node invasion in 5 and in one patient no residual disease. In whole group total 11 lymph node invasion and 6 distant metastasis were identified. Primary site of patient who had lymph node metastasis weren't found with PET/CT. Conclusion: Because of the capability of whole body definition and accurate lymph node staging of PET/CT and remarkable FDG affinity of head and neck tumors, PET/CT is a preferable imaging method. Considering general limitations and limitations which are specific to head and neck region of PET/CT; PET/CT can be used for staging and identification of head and neck tumors with high accuracy.
Bookmark/Search this post with
Abstract (Original Language): 
Amaç: Baş ve boyun tümörlerinde evrelemede PET/BT giderek artan oranda rutin kullanıma girmektedir. PET/BT tüm vücudu tarama olanağı sağlaması ve baş-boyun tümörlerinde tutulum göstermesi ve lenf nodlarını doğru bir şekilde karakterize etmesi bakımından evrelemede kolaylık sağlamaktadır. Bu çalışma ile baş ve boyun tümörleri olan hastalarda evrelemede PET/BT'nin önemini araştırdık. Gereç ve Yöntem: Çalışmaya baş ve boyun tümörü olan 19 hasta (11 E, 8 K; ortalama yaş;50.4±17) dahil edilmiştir. Hastalara yapılan PET/BT sonuçları altın standart takip sonucu veya histopatoloji alınarak değerlendirilmiştir. Bulgular: Çalışmaya dahil edilen hastalardan 3 tanesi tiroid karsinomu, 3'ünde larenks karsinomu, 1'inde boyunda lenfadenopati etyolojisi, 3'ünde dil-damakta kitle, 3'ünde boyunda kitle karakterizasyonu, 2'sinde proksimal özefagus karsinomu, 3'ünde parotis tümörü ve 1 hastada yüzde malign melanom nedeniyle PET/BT yapılmıştır. PET/BT hastalardan 4 tanesinde rezidü/nüks ve 9'unda kitle lezyonu tanımlamış, 5'inde lenf nodu yayılımını ve bir hastada rezidü veya nüks olmadığını göstermiştir. Bütün hasta grubunda toplam 11 hastada lenf nodu invazyonu ve 6 hastada uzak metastazı göstermiştir. Patolojik lenfadenopati nedeniyle gönderilen bir hastada ise primeri belirleyememiştir. Sonuç: PET/BT baş boyun tümörlerinin değerlendirilmesinde rahatlıkla kullanılabilecek bir yöntemdir. Yöntemin gerek bu bölgeye özgü gerekse genel sınırlılıkları göz önünde bulundurularak yüksek doğrulukla kitle tanımlama ve evreleme için kullanılabilir.
FULL TEXT (PDF): 
PDF icon bt.pdf
  • 4
194-198
  • Turkish

REFERENCES

References: 

1. Schwartz DL, Rajendran J, Yueh B, et al. Staging of head and neck squamous cell cancer with extended-field FDG-PET.Arch Otolaryngol Head Neck Surg 2003; 129: 1173¬1178.
2. Dennington ML, Carter DR, Meyers AD. Distant metastases in head and neck epidermoid carcinoma. Laryngoscope 1980; 90:
196-201.
3. Black RJ, Gluckman JL, Shumrick DA. Screening for distant metastases in head and neck cancer patients. Aust N Z J Surg
1984; 54: 527-530.
4. Kumar R, Mavi A, Bural G, Alavi A. Fluorodeoxyglucose-PET in the management of malignant melanoma. Radiol Clin
North Am 2005; 43: 23-33.
5. Kitagawa Y, Nishizawa S, Sano K, et al. Prospective comparison of 18F-FDG PET with conventional imaging modalities (MRI, CT, and 67Ga scintigraphy) in assessment of combined intraarterial chemotherapy and radiotherapy for head and neck carcinoma. J Nucl Med 2003; 44: 198-206.
6. Di Martino E, Nowak B, Hassan HA, et al. Diagnosis and staging of head and neck cancer: a comparison of modern imaging modalities (positron emission tomography, computed tomography, color-coded duplex sonography) with panendoscopic and histopathologic findings. Arch Otolaryngol Head Neck Surg 2000; 126: 1457-1461.
7. Basu D, Siegel BA, McDonald DJ, Nussenbaum B. Detection of occult bone metastases from head and neck squamous cell carcinoma: impact of positron emission tomography computed tomography with fluorodeoxyglucose F 18. Arch Otolaryngol
Head Neck Surg 2007; 133: 801-805.
8. Gordin A, Daitzchman M, Doweck I, et al. Fluoro-deoxyglucose-positron emission tomography /computed tomography imaging in patients with carcinoma of the larynx: diagnostic accuracy and impact on clinical management.
Laryngoscope 2006; 116: 273-278.
197
Fırat Tıp
Dergis
i 2011; 16(4): 194-198
9. Ha PK, Hdeib A, Goldenberg D, et al. The role of positron emission tomography and computed tomography fusion in the management of early-stage and advanced-stage primary head and neck squamous cell carcinoma. Arch Otolaryngol Head
Neck Surg 2006; 132: 12-16.
10. Schoder H, Yeung HW, Gonen M, et al. Head and neck cancer: clinical usefulness and accuracy of PET/CT image
fusion. Radiology 2004; 231: 65-72.
11. Demirci U, Coskun U, Akdemir UO, et al. The Nodal
Standard Uptake Value (SUV) as a Prognostic Factor in Head and Neck Squamous Cell Cancer. Asian Pac J Cancer Prev
2011; 12: 1817-1820.
12. Liao CT, Wang HM, Huang SF, et al. PET and PET/CT of the neck lymph nodes improves risk prediction in patients with squamous cell carcinoma of the oral cavity. J Nucl Med 2011; 52: 180-187.
13. Connell CA, Corry J, Milner AD, et al. Head Neck. Clinical
impact of, and prognostic stratification by, F-18 FDG PET/CT in head and neck mucosal squamous cell carcinoma. Head
Neck 2007; 29: 986-995.
14. Haerle SK, Schmid DT, Ahmad N, Hany TF, Stoeckli SJ. The value of (18) F-FDG PET/CT for the detection of distant
Koç ve Balcı
metastases in high-risk patients with head and neck squamous cell carcinoma. Oral Oncol 2011; 47: 653-659.
15. Xu GZ, Guan DJ, He ZY. (18) FDG-PET/CT for detecting distant metastases and second primary cancers in patients with head and neck cancer. A meta-analysis. Oral Oncol 2011; 47:
560-565.
16. Law A, Peters LJ, Dutu G, Rischin D, Lau E, Drummond E, Corry J. The utility of PET/CT in staging and assessment of treatment response of nasopharyngeal cancer. J Med Imaging Radiat Oncol 2011; 55: 199-205.
17. Kim SY, Kim JS, Doo H, et al. Combined [18F] fluorodeoxyglucose positron emission tomography and computed tomography for detecting contralateral neck metastases in patients with head and neck squamous cell
carcinoma. Oral Oncol 2011; 47: 376-380.
18. Maldonado A, Gonzâlez-Alenda FJ, Alonso M, Sierra JM.
PET/CT in clinical oncology. Clin Transl Oncol 2007; 9: 494¬505.

Thank you for copying data from http://www.arastirmax.com