Buradasınız

Anasayfa » Content

İmipramin Kullanımına Bağlı Konvülsiyon Olgusu

Convulsion Due To Use Imipramine: A Case Report

Journal Name:

  • Fırat Tıp Dergisi

Publication Year:

  • 2012

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
An eight-year-old girl patient was admitted to hospital with generalized tonic-clonic seizure without fever. It was established from the patient's medical history that she was using imipramine 10 mg (0.41 mg/kg/day) for a duration of 20 days for enuresis nocturna. There was no specialty in the personal or family history. Her physical examination was normal. The serum electrolytes, liver function tests, renal function tests and brain magnetic resonance imaging were normal. The patient's seizure was considered to be linked to imipramine. Imipramine was stopped. The patient is being follow-up for six months without receiving anticonvulsant therapy. With this case, we would like to emphasize that imipramine could have caused the convulsion.
Bookmark/Search this post with
Abstract (Original Language): 
Sekiz yaşında kız hasta ateşsiz dönemde jeneralize tonik klonik nöbet geçirme şikayetiyle getirildi. Hikâyesinden hastanın 20 gündür enürezis noktur-na nedeniyle imipramin tablet 10 mg/gün (0.41 mg/kg/gün) kullandığı öğrenildi. Özgeçmişi ve soy geçmişinde özellik yoktu. Fizik muayenesi normal idi. Serum elektrolitleri, karaciğer ve böbrek fonksiyon testleri, beyin magnetik rezonans görüntülemesi normaldi. Hastanın nöbetinin imipramine bağlı olduğu kabul edildi ve imipramin kesildi. Hasta halen antikonvülsan tedavi almaksızın 6 aydır takip edilmektedir. Bu vaka dolayısıyla imipra-minin konvülsiyon yapabileceğini vurgulamak isteriz.
FULL TEXT (PDF): 
PDF icon arastirmax-imipramin-kullanimina-bagli-konvulsiyon-olgusu.pdf
  • 4
248-249
  • Turkish

REFERENCES

References: 

1. Elder JS. Voiding Dysfunction. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF (eds): 18th edition. Nelson Textbook of Pediatrics, WB Saunders Co, Phiadelphia 2007;
2249-53.
2. Gera T, Seth A, Mathew J. Nocturnal enuresis in children. Internet J Pediatr Neonatol 2001; 12: 1-12.
3. Koella WP, Glatt A, Klebs K, Dürst T, Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline. Bio. Psychiatry
1979; 14: 485-97.
4. Rosenstein DL, Nelson JC, Jacobs SC, Seizures associated with antidepressants. J Clin Psychiatry 1993; 54: 289-99.
5. Greenbaum L. Maintenance and Replacement Therapy. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF (eds): 18th edition. Nelson Textbook of Pediatrics, WB Saunders Co,
Phiadelphia 2007; 339-57.
6. Tahmaz L, Kibar Y, Yıldırım I, Ceylan S. Combination therapy of Imipramine with Oxybutynin in children enuresis nocturna. Urol Int 2000; 65: 135-9.
7. Gepertz S, Neveus T. Imipramine for therapy resistant enuresis: a retrospective evaluatiun. J Urol 2004; 171: 2607¬10.
8. Meadour S. Enuresis. Pediatrics Kidney Disease. Chester M. Edelmann, JR (eds) 1992; 2015-21.
9. Neyzi O,
Ertuğru
l T, Ekşi A. Psikososyal gelişme ve sorunlar, çocuğun ruhsal gelişimi, Enürezis, Pediatri. İstanbul: Nobel
Tıp Kitabevleri, 2002; 1420-1.
10. Shaffer D. Enuresis. In: Rutter M, Taylor E, Hersov L (eds). Child and Adolescent Psychiatry, London: Blackwell Science 1994; 505-19.
11. Hagglöf B, Andren O, Bergstrom E, Marklund L, Wendelius M. Self-Esteem in children with nocturnal enuresis and urinary ıncontinence. Eur Urol 1998; 33: 16-9.
12. Richelson E, Nelson A. Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. J
Pharmacol Exp Ther 1984; 230: 94-102.
13. Kanba S, Richelson E, Antidepressant interactions with neurotransmitter receptors in vitro: prediction of potential side effects. In: O'Brien, R.A. (Ed.), Receptor Binding in Drug Research. Progress in Clinical Pharmacology, vol. 5. Dekker,
New York 1986; 429-47.
14. Ago J, Ishikawa
T
, Matsumoto N, Ashequr Rahman M, Kamei C. Mechanism of imipramine-induced seizures in amygdala-
kindled rats. Epilepsy Res 2006; 72: 1-9.

Thank you for copying data from http://www.arastirmax.com