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Helicobacter pylori enfeksiyonu tanısında tanısal yöntemler

Diagnostic methods of Helicobacter pylori infection

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2008

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Abstract (2. Language): 
Helicobacter pylori is a spiral, gram negative bacterium and found to be associated with gastritis, peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. Thus there is an increasing importance of the treatment of Helicobacter pylori and thereby a great need for simple and accurate diagnostic methods. Helicobacter pylori infection can be diagnosed by invasive and non-invasive techniques. Invasive diagnostic methods require mucosal biopsy during endoscopy and then subjecting them to culture, rapid urease test, polymerase chain reaction or histologic analysis. Non-invasive methods include antibody detection (serology), stool antigen and urea breath tests.
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Abstract (Original Language): 
Helicobacter pylori, spiral yapısında gram negatif bir bakteridir ve gastrit, peptic ülser, gastrik adenokarsinoma ve MALT lenfoma ile ilişkili olduğu gösterilmiştir. Bu nedenle tedavisi gittikçe önem kazanmaktadır ve basit, doğru tanısal yöntemlere gereksinim vardır. Helicobacter pylori enfeksiyonu tanısı invaziv ve noninvaziv yöntemler ile konulabilir. İnvaziv tanısal yöntemler endoskopik işlem sırasında biyopsi alınmasını ve bu doku parçalarının daha sonra kültür, hızlı üreaz testi, polimeraz zincir reaksiyonu veya histolojik analize tabi tutulmasını gerektirir. Noninvaziv yöntemler ise, serumda antikor saptanması (seroloji), gaitada antijen ve üre nefes testlerini içerir.
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  • English

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