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Rekürren maternal CMV enfeksiyonları ne kadar masum? Sitomegalik inklüzyon hastalığı olan bir yenidoğanın sunumu

How much innocent are recurrent maternal CMV infections? A case report of a newborn with cytomegalic inclusion disease

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2008

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Abstract (2. Language): 
It is known that cytomegalic inclusion disease due to congenital CMV infection almost always occurs after a primary infection of the mother during her pregnancy who has not preconceptual immunity, and screening tests mainly aim to identify these primary infections. However, it has been reported that there are no significant differences in the incidence of cytomegalic inclusion disease, clinical presentation of the disease and rate of long-term sequela occuring after primary or recurrent maternal infection. By presenting cytomegalic inclusion disease which developed in the newborn of a mother with preconceptual immunity in this article, we aimed to emphasize that recurrent maternal CMV infection may result in serious problems on the contrary to the common knowledge. Additionally we aimed to point out the necessity of making screening tests in a manner to identify maternal primary as well as recurent infections in countries like ours in where seroprevalence of CMV approaches to 100% in early ages.
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Abstract (Original Language): 
Konjenital CMV enfeksiyonuna bağlı sitomegalik inklüzyon hastalığının hemen her zaman, gebelik öncesinde CMV immünitesi olmayan bir annenin gebeliği sırasında geçirdiği primer bir enfeksiyon sonucu oluştuğu bilinmektedir ve tarama testleri de daha çok bu primer enfeksiyonu saptamayı amaçlamaktadır. Bununla birlikte, primer veya rekürren maternal enfeksiyon sonucu sitomegalik inklüzyon hastalığı oluşması insidansında, hastalığın ortaya çıkış kliniğinde ve uzun süredeki sekel oranında anlamlı bir fark olmadığı da bildirilmektedir. Bu yazıda, gebeliği öncesinde CMV immünitesi olan bir annenin yenidoğanında ortaya çıkan sitomegalik inklüzyon hastalığını sunarak, rekürren maternal CMV enfeksiyonunun bilinenin aksine önemli sonuçlar doğurabileceğini vurgulamayı amaçladık. Ayrıca ülkemiz gibi CMV seroprevalansının erken yaşlarda %100'e ulaştığı ülkelerde, tarama testlerinin primer kadar rekürren maternal CMV enfeksiyonlarını da saptamayı amaçlayacak şekilde yapılmasının gerektiğine dikkat çekmek istedik.
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  • 1
34-38
  • Turkish

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