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Yetişkin blastemal Wilms tümörüne benzerlik gösteren renal primer primitif nöroektodermal tümörün immünohistokimyasal özellikleri: olgu sunumu

The immunohistochemical features of the renal primary primitive neuroectodermal tumor mimicking adult blastemal Wilms tumor: a case report

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2009

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Primary primitive neuroectodermal tumor of the kidney is a rare and aggressive tumor. Its distinction from other primary renal tumors is clinically important due to different therapeutic management. A 44-year-old man was admitted to the hospital with left flank pain and hematuria. In computerized tomography, a mass in left kidney was detected and nephrectomy was performed. Microscopically the tumor was composed of small round cells. Immunohistochemically, diffuse strong positivity for CD 99 (MIC2) and NSE, and focal positivity for Wilms tumor 1 were determined in the tumor cells. In this report, a rare renal primary primitive neuroectodermal tumor showing both CD99 and Wilms tumor 1 expression is presented
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Abstract (Original Language): 
Böbreğin primer primitif nöroektodermal tümörü seyrek görülen agresif bir tümördür. Farklı tedavi yaklaşımları nedeniyle, klinik olarak bu tümörün diğer primer renal tümörlerden ayırımı önemlidir. Kırk dört yaşında erkek hasta sol yan ağrısı ve hematüri şikayetleri ile hastaneye başvurdu. Bilgisayarlı tomografide sol böbrekte kitle saptandı ve nefrektomi uygulandı. Mikroskopik olarak, tümör küçük yuvarlak hücrelerden oluşmaktaydı. İmmünohistokimyasal olarak, tümör hücrelerinde yaygın ve kuvvetli CD 99 (MIC2) ve NSE, fokal Wilms tümör 1 pozitifliği saptandı. Bu yazıda CD 99 ve Wilms tümör 1 ekspresyonu gösteren ve seyrek görülen renal primer primitif nöroektodermal tümör olgusu sunulmuştur.
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  • 2
112-115
  • English

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