Buradasınız

İntrakraniyal dev lipom ve epilepsi: olgu sunumu

Intracranial giant lipoma and epilepsy: a case report

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
Intracranial lipomas are very rare tumors with an incidence of approximately 0.1% of diagnosed brain tumors and 0.08% of tumors found on autopsy. Lipomas, classified in conjenital malformations of the central nervous system, constitute 0.06-0.46% of intracranial lesions. These tumors are usually asymptomatic, and detected during radiological investigations and autopsy. Intracranial lipomas usually present with headache, epileptic seizures, psychomotor retardation and cranial nerve paralysis. A 20-yearold male patient admitted to our department because of headache. He had the diagnosis of epilepsy (under control) since 12-year-old. His neurologic examination and neurophysiologic investigations were normal. His brain magnetic resonance imaging demonstrated a 5.5x6x8 cm sized interhemispheric mass lesion in fat intensity in all secanses and callosal agenesis. This article was presented to emphasize the co-existence of intracranial lipoma, callosal agenesis and epilepsy in the light of similar cases in the literature.
Abstract (Original Language): 
ntrakraniyal lipomlar tanı konmuş beyin tümörlerinin yaklaşık %0.1’i ve otopsi olgularının %0.08’i ile oldukça nadir görülen tümörlerdir. Santral sinir sisteminin konjenital malformasyonları içerisinde sınıflandırılan lipomlar, intrakraniyal lezyonların %0.06-0.46’sını oluşturmaktadır. Genellikle asemptomatik olup, radyolojik incelemeler veya otopsi esnasında bulunur. İntrakraniyal lipomlar genellikle başağrısı, epileptik nöbet, psikomotor retardasyon ve kraniyal sinir paralizisi gibi klinik bulgularla kendini gösterir. Yirmi yaşında erkek hasta, başağrısı yakınması ile polikliniğimize müracaat etti. Hastanın öyküsünde 12 yaşından beri kontrol altında olan epilepsi tanısı mevcuttu. Nörolojik muayenesi ve nörofizyolojik incelemeleri normal sınırlarda olan hastanın beyin manyetik rezonans görüntülemesinde interhemisferik bölgede tüm sekanslarda yağ ile izointens görünüm ile karakterize yaklaşık 5.5x6x8 cm boyutlarında dev lipom ile uyumlu kitle lezyonu ve kallozal agenezi izlendi. Epilepsi ile intrakraniyal lipom ve kallozal agenezi birlikteliğini literatürdeki benzer olgular ışığında vurgulamak için bu makale sunulmuştu
256-258

REFERENCES

References: 

Kaynaklar
1. Baesa SS, Higgins MJ, Ventureyra EC. Dorsal brain
stem lipomas: case report. Neurosurgery 1996; 38:
1031-1035.
2. Truwit CL, Barkovich AJ. Pathogenesis of intracranial
lipoma: an MR study in 42 patients. AJR 1990; 155:
855-864.
3. Rubio G, Garcia Guijo C, Mallada JJ. MR and CT
diagnosis of intracranial lipoma. AJR 1991; 157: 887.
4. Wilberger JE Jr, Abla A, Rothfus W. Lipoma of the septum
pellucidum: case report. J Comput Assist Tomogr 1987;
11: 79-82.
5. Zettner A, Netsky M. Lipoma of the corpus callosum. J
Neuropathol Exp Neurol 1960; 119: 305-319.
6. Verga P. Lipoma ed osteolipomi della pia madre. Tumori
1929; 15: 321-357.
7. List C,Holt J,Everett M. Lipoma of the corpus callosum.
A clinicopathologic study. AJNR 1946; 55: 125-134.
8. Leinbrock LG, Deans WR, Block S, Shuman RM,
Skultety FM. Cerebellopontine angle lipoma: a review.
Neurosurgery 1983; 12: 697-699.
9. Kazner E, Stochdorph O, Wende S. Intracranial lipoma:
diagnostic and therapeutic considerations. J Neurosurg
1980; 52: 234-245.
10. Maiuri F, Corriero G, Gallicchio B, Simonetti L. Lipoma of
the ambient cistern causing obstructive hydrocephalus.
J Neurosurg Sci 1987; 31: 53-58.
11. Friedman RB, Segal R, Latchaw RE. Computerized
tomographic and magnetic resonance imaging of
intracranial lipoma. J Neurosurg 1986; 65: 407-410.
12. Paterman SB, Steiner RE, Bydder GM. Magnetic
resonance imaging of intracranial tumors in children
and adolescents. AJNR 1984; 5: 703-709.
13. Doll A, Abu Eid M, Kehrli P, et al. Aspects of FLAIR, 3DCISS and diffusion-weighted MR imaging of intracranial
epidermoid cysts. J Neuroradiol 2000; 27: 101-106.
14. Rokitansky C Lehrbuch der pathologischen Anatomie
1856; p 468.
15. Britt PM, Bindal AK, Balko MG, Yeh HS. Lipoma of
the cerebral cortex: case report. Acta Neurochir (Wien)
1993; 121: 88–92.
16. Gastaut H, Regis H, Gastaut JL, Yermenos E, Low MD.
Lipomas of the corpus callosum and epilepsy. Neurology
1980; 30: 132–138.
17. Loddenkemper T, Morris HH 3rd, Diehl B, Lachhwani
DK. Intracranial lipomas and epilepsy. J Neurol 2006;
253: 590–593.
18. Tahmouresie A, Kroll G, Shucart W. Lipoma of the
corpus callosum. Surg Neurol 1979; 11: 31–34

Thank you for copying data from http://www.arastirmax.com