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Obez çocuklarda metabolik sendrom prevalansı ve kardiyovasküler risk faktörlerinin sıklığı

The prevalence of metabolic syndrome and frequency of cardiovascular risk factors in obese children

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2010

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Frequency of metabolic syndrome and cardiovascular risk factors were investigated in obese children and adolescents in this study. Two hundred and eight children with a mean age of 9.9±2.5 years were enrolled in the study. WHO criteria were used in the diagnosis of metabolic syndrome. Hypertrigliceridemia, hypercholesterolemia, high LDL cholesterol, low HDL cholesterol, hypertension and impaired glucose tolerance were detected in 66 (31.7%), 30 (14.4%), 26 (12.5%), 7 (3.3%), 34 (16.3%) and 34 (16.3%) of the cases, respectively. The frequency of cardiovascular risk factors was not significantly different between the female and male obese children (p>0.05). Significantly lower HDL cholesterol levels were noted in prepubertal obese children when compared to pubertal obese children (7% and 0%, respectively). Of all the cases, insulin resistance was present in 43.7% (n=91). Metabolic syndrome was detected in 27.4% and 21.4% of male obese and female obese children, respectively. Metabolic syndrome was present in 22 (21.7%) and 30 (28%) of prepubertal obese cases and adolescent obese cases, respectively (p>0.05). Of all the cases, 25% (n=52) had metabolic syndrome. The frequency of metabolic syndrome did not show significant differences between female obese and male obese children, and prepubertal obese and pubertal obese cases (p>0.05). Of the cardiovascular risk factors in the present study, insulin resistance and hypertrigliceridemia were particularly more frequent in obese children and adolescents. The prevalence of metabolic syndrome is high in obese children and adolescents. This situation is a great risk for our children who are the future of our country.
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Abstract (Original Language): 
Bu çalışmada, obez çocuk ve adölesanlarda metabolik sendrom ve kardiyovasküler risk faktörlerinin sıklığı araştırıldı. Yaş ortalaması 9.9±2.5 yıl olan 208 obez çocuk değerlendirildi. Metabolik sendrom tanısı için WHO kriterleri kullanıldı. Olguların 66’sında (%31.7) hipertrigliseridemi, 30’unda (%14.4) hiperkolesterolemi, 26’sında (%12.5) LDL-kolesterol yüksekliği, 7’sinde (%3.3) HDL-kolesterol düşüklüğü, 34’ünde (%16.3) hipertansiyon, 34’ünde (%16.3) bozulmuş açlık glikozu saptandı. Kardiyovasküler risk faktörlerinin sıklığı kız ve erkek obezler arasında istatistiksel olarak anlamlı farklılık göstermiyordu (p>0.05). HDL-kolesterol düşüklüğü prepubertal obezlerde pubertal obezlere göre daha sık idi (sırasıyla %7 ve %0, p<0.05). Tüm olguların %43.7’sinde (n=91) insülin direnci vardı. Metabolik sendrom, obez erkek olguların %27.4’ünde, obez kızların %21.4’ünde tespit edildi (p>0.05). Prepubertal olguların 22’sinde (%21.7), adölesan obezlerin ise 30’unda (%28.0) metabolik sendrom saptandı (p>0.05). Tüm olguların ise %25’inde (n=52) metabolik sendrom vardı. Metabolik sendrom sıklığı kız/erkek ve prepubertal/pubertal obezlerde farklılık göstermiyordu (p>0.05). Çalışmamı- zın sonuçlarına göre kardiyovasküler risk faktörlerinden özellikle insülin direnci ile hipertrigliseridemi, obez çocuk ve adölesanlarda oldukça sık görülmektedir. Obez çocuk ve adölesanlarda metabolik sendrom prevalansı yüksektir. Bu durum ülkemizin geleceği olan çocuklarımız için büyük risk oluşturmaktadır.
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  • 1
32-35
  • Turkish

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