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Tip 2 diyabetli hastalarda doku Doppler görüntüleme yöntemi ile atriyal elektromekanik eşleşme süresinin tayini

The assessment of atrial electromechanic coupling time by using tissue Doppler imaging in patients with type 2 diabetes mellitus

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2010

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Determination of atrial electromechanical coupling time interval by tissue Doppler imaging in diabetic patients may provide important information about the pathophysiology of diabetes mellitus-atrial fibrillation relationship. Twenty two healthy individuals (Control group; Group 1), 27 patients with diabetes mellitus of <5 years’ duration (Group 2) and 18 patients with diabetes mellitus of ≥5 years’ duration (Group 3) were enrolled in the study. Time intervals from the beginning of electrocardiographic p wave to the onset and peak of atrial contraction waves obtained via lateral and septal left atrial walls were measured by using color tissue Doppler imaging from the apical four chamber view. These time intervals were defined as atrial electromechanical coupling interval begin (AECI begin ) and AECI peak. Moreover, mitral inflow velocities by pulsed-wave Doppler (E wave, A wave and E deceleration time) and annular velocities by color tissue Doppler imaging (S’, E’, A’) were also measured. There were no significant differences among the groups in terms of AECI begin and AECI peak. However, septal mitral annular E’ wave velocity was significantly lower in Group 3 compared to the other groups. In addition, lateral mitral annular E’ wave velocity was significantly lower in Group 3 compared to Group 1. Although we were not able to find any significant differences for both AECI begin and AECI peak values among the groups, we demonstrated that myocardial diastolic functions were significantly impaired in patients with diabetes of long duration as reflected by lower E’ velocities and increased E/E’ ratios.
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Abstract (Original Language): 
Diyabetik hastalarda doku Doppler görüntüleme yöntemi ile atriyal elektromekanik eşleşme süresinin tayini, diyabet-atriyal fibrilasyon ilişkisinin nedenleri hakkında önemli bilgiler sağlayabilir. Sağlıklı 22 birey (kontrol grubu; Grup 1), 5 yıldan daha kısa süredir diyabeti olan 27 hasta (Grup 2) ve 5 yıl veya daha uzun süredir diyabeti olan 18 hasta (Grup 3) çalışmaya alındı. Apikal 4 oda görüntüsünden, renkli doku Doppler görüntüleme yöntemi ile elektrokardiyografideki p dalgasının başlangıcından sol atriyum lateral ve septal duvarları üzerinden elde edilen atriyal kasılma dalgalarının başlangıcına ve zirvesine kadar olan süreler ölçüldü. Bu süreler atriyal elektromekanik eşleşme süresi (AEESbaşlangıç ) ve AEES zirve olarak tanımlandı. Ayrıca, pulsed-wave Doppler yöntemiyle mitral içeakım hızları (E dalgası, A dalgası, E deselerasyon zamanı) ve renkli doku Doppler görüntüleme yöntemiyle mitral anulus hızları (S’, E’, A’) da ölçüldü. AEES başlangıç ve AEES zirve açısından gruplar arasında anlamlı farklılık saptanmadı. Ancak, Grup 3’deki septal mitral anulus E’ dalgası hızının diğer gruplara göre anlamlı derecede daha düşük olduğu bulundu. Ayrıca, Grup 3’deki lateral mitral anulus E’ dalgası hızının da Grup 1’e göre anlamlı derecede daha düşük olduğu izlendi. Her ne kadar AEES başlangıç ve AEES zirve değerleri açısından gruplar arasında anlamlı farklılık bulamamış olsak da, azalmış E’ hızları ve artmış E/E’ oranlarına dayanarak, uzun süreli diyabet hastalarında miyokardiyal diyastolik fonksiyonların ciddi derecede bozulduğunu gösterdik
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  • 1
23-27
  • Turkish

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