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İkiz olgu raporunda tuz kaybının farklı klinik yansıması: izole hipoaldosteronizm

A different clinical presentation of salt wasting in the case report of twins: selective hypoaldosteronism

Journal Name:

  • Gülhane Tıp Dergisi

Publication Year:

  • 2010

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Abstract (2. Language): 
Selective hypoaldosteronism is a rare cause of life-threatening salt wasting in the neonatal period. Patients are most frequently diagnosed with the clinical signs of aldosterone deficiency during the first week of life. In this case report, twin premature newborns who were diagnosed with different clinical presentations with hyperkalemia and hyponatremia in the first and 5th months of life are presented. The electrolyte values of the twin cases diagnosed to have selective hypoaldosteronism improved rapidly after administration of oral salt (NaCl) and fludrocortisone treatments. It should be kept in mind that selective hypoaldosteronism should be considered in the differential diagnosis of salt-losing pathologies in the neonatal period, and patients may present with different clinical findings in the first month of life.
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Abstract (Original Language): 
İzole hipoaldosteronizm, yenidoğan döneminde yaşamı tehdit eden tuz kaybının nadir bir nedenidir. Hastalar sıklıkla yaşamın ilk haftasında aldosteron eksikliğinin klinik bulguları ile tanı alırlar. Bu olgu sunumunda, hiperkalemi ve hiponatreminin eşlik ettiği yaşamın 1. ve 5. ayında farklı klinik bulgularla tanı alan ikiz prematüre olgular sunulmuştur. İzole aldosteron eksikliği tanı- sı alan ikiz olgulara oral tuz (NaCl) ve fludrokortizon tedavisi uygulanması sonrası elektrolit değerleri hızla normale döndü. İzole aldosteron eksikliği, yenidoğan döneminde tuz kaybı ile giden patolojilerin ayırıcı tanısında dü- şünülmeli ve yaşamın ilk ayında farklı klinik bulgularla başvurabilecekleri de akılda tutulmalıdır.
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  • 2
143-147
  • Turkish

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