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Kronik böbrek yetmezliği, diyaliz ve böbrek naklinin cinsel ve üreme işlevleri üzerindeki etkileri

The effects of chronic renal failure, dialysis and kidney transplantation on sexual and reproductive functions

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Abstract (2. Language): 
The uremic milieu plays an important role in the development of sexual dysfunction in chronic renal failure. High FSH and LH and low testosterone levels are reported in uremic men and testosterone level returns to normal after a successful kidney transplantation. Spermatogenic abnormalities and loss of libido and potency associated with a defect in testosterone biosynthesis have been reported in about half of hemodialysis patients. It is well established that libido and potency, which are of disorders of sexual dysfunction persisting during hemodialysis in men with uremia resolve after renal transplantation. In this article pathophysiology of sexual dysfunction is firstly reviewed, and later erectile dysfunction and its treatment are discussed.
Abstract (Original Language): 
Kronik böbrek yetmezliğinde cinsel işlev bozukluğunun ortaya çıkmasında üremik ortam önemli rol oynar. Üremik erkeklerde yüksek FSH, LH ve dü- şük testosteron seviyeleri bildirilmektedir ve başarılı böbrek nakli sonrası testosteron seviyesinin normal sınırlara geldiği anlaşılmıştır. Hemodiyaliz hastalarının yaklaşık yarısında, spermatogenik anormallikler ve testosteron biyosentezinde eksiklikle ilişkili libido ve potens kaybı meydana gelir. Üremik erkeklerde hemodiyalizin devamı boyunca sürekli olarak görülen cinsel işlev bozukluklarından libido ve potensin böbrek nakli sonrası geriye döndüğü ortaya konmuştur. Bu derlemede kronik böbrek yetmezliği hastalarında üreme işlevi yetersizliğinin patofizyolojisi öncelikle incelenmiş, sonra erektil işlev bozukluğu ve tedavisi tartışılmıştır.
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