Buradasınız

Anasayfa » Content

SPORCULARDA C VİTAMİNİ ALIMININ VE AKUT EGZERSİZİN PLAZMA LİPİD DEĞERLERİ ÜZERİNE ETKİSİNİN ARAŞTIRILMASI

EFFECTS OF VİTAMİN C AND ACUTE EXERCISE ON PLASMA LIPIDS

Journal Name:

  • Hacettepe Üniversitesi Spor Bilimleri Dergisi

Publication Year:

  • 1996

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Today exercise is used in most of the cardiovasculer rehabilitation units. The positive effect of exercise in preventing cardiovasculer disease is believed to be due to the increase in plasma HDL levels. Vitamin C was reported by some authors as an agent which increses the plasma HDL levels. However there are only a few investigations on this issue in the literature. The aim of the present investigation was to evaluate the effects of exercise and vitamin C on plasma lipid levels. The subjects consists of thes study were 9 active sportsmen with the average age of 22.1 years. All the subjects exercised for one hour on a cycle ergometer at an intensity of individual (% 75 max VO2 level) and blood samples were obtained before and just after the acute exercise. Subjects were given with vitamin C (2 gr. per day) for three months and same procedures were repeated. As a result plasma total cholesterol (TC) and high dansity lipoprotein HDL levels increased due to the acute exercise. After loading with vitamin C significant increase was observed only in the plasma HDL level (p<0.05). Trigliserid (TG), TC, HDL, very low dansity lipoprotein (VLDL) levels were found to be increased in the C vitamin loaded group following the acute exercise (p<0.05). No significant difference was observed between the two groups following the acute exercisein terms of blood lipids parameters
Bookmark/Search this post with
Abstract (Original Language): 
Günümüz kardiyovasküler hastalıkların tedavisinde ve korunmada egzersiz yaygın olarak kullanılmaktadır. Egzersizin bu olumlu etkisinin plazma yüksek dansiteli lipprotein (HDL) düzeyini artırmasından kaynaklandığı bazı araştırıcılarca belirtilmektedir. C vitaminin de plazma HDL düzeyi üzerine olumlu katkıları olduğuna dair görüşler vardır ancak bu konu tam olarak açıklığa kavuşmamıştır. Bu çalışma egzersiz ve C vitamininin plasma lipidleri üzerindeki etkisinin incelenmesini amaçlamıştır. Çalışma materyali sporla uğraşan, yaş ortalamaları 22.1 olan 9 erkek sporcudan alınan venöz kan örneklerinden oluşmuştur. Bireyler %75 max VO2 seviyesinde bir saat süre ile bisiklet ergometresinde eğzersize tabi tutulmuş, venöz kan örnekleri egzersiz öncesi ve egzersizden hemen sonra alınmıştır. Deneklere günde 2 g doz olarak üç hafta süre ile C vitamini yüklemesi yapılmış ve aynı işlemler üç hafta sonunda tekrarlanmıştır. Sonuç olarak akut egzersize bağlı olarak total kolesterol (TC) ve HDL düzeyinde istatistiksel olarak anlamlı artış bulunmuştur (p<0.01) C vitamini yüklemesini takiben yapılan akut egzersiz sonucu ise tiglise-rid (TG), TC, HDL ve çok düşük dansiteli lipopretein (VLDL) düzeylerinde istatistiksel olarak anlamlı artış bulunmuştur (p<0.05). Üç haftalık C vitamini alımı sonucu ise yalnızca HDL düzeyinde anlamlı artış saptanmıştır (p<0.05). C vitamini yüklemesi öncesi ve sonrası akut egzersiz sonuçları karşılaştırıldığında ise kan lipid parametreleri açısından anlamlı bir fark bulunamamıştır.
FULL TEXT (PDF): 
PDF icon arastrmx_152775_7_pp_3-12.pdf
  • 2
3-12
  • Turkish

REFERENCES

References: 

1. Astrand PO, Rodahl K; Textbook ol work physiology, Mc Graw- Hill Co 112-115, Newyork, 1986
2. Bates CJ, Mandai AR, Cole TJ; HDL-C and vitamin C status. Lancet 611, 1977.
3. Bazzarre TL, Scarpino A. Sigmon R, Marquart LF, Wu SM, Izurieta M: Vitamin -mineral supplement use and nutritional status of athelets. J Am Coll Nutr 12 (2): 162-169, 1993.
4. Berg A, Johns J. Baumtark M, Meul J; HDL-C changes during and after intersive long lasting exercise. Int J Sports Med 2: 121-123, 1981.
5. Berger G, Griffiths M, Acute effect of moderate exercise on plasma lipoprotenis paramètres. Int J Sports Med 8:336-341, 1987
6. Bolton SC, Woodward M, Smith WCS, Tunstall PH: Dietary and non-dietary predictors of serum total and HDL cholesterol in men and women: Results from the Scottish Heart Health Study, Int J Epidemiol 20; 95-104,, 1991.
7. Church JP, Judd JT, Young CW, Kelsay WW: Relationships among dietary consituents and specific serum clinical componenets of subjects eating self-selected diets. Am J Clin Nutr 40: 1388-1344. 1994.
8. Cordova C, Musca A, Viola F, Perrone A, Alessandri C; Influence of ascobic acid on platelet aggregation in vitro and in vivo. Atherosclerosis 4; 15-19, 1982.
9. Cullinane E, Lazarus B, Thompson PD, Saratelli A, Herbert PN; Acute effects of a single exercise session on serum lipids in untrained men. Clin Chim Acta 109; 341-344, 1981.
10. Enstrom JE, Kanim LE, Klein MA: Vitamin C intake and mortality among a sample of the US population. Epidemiology 3; 194-202, 1992.
11. Esterbauer H, Dieber RM, Striegl G, Waeg G: Role of vitamin E in preventing the oxidation of LDL. Am J Clin Nutr 53; 314 S, 1991
12. Frei B, England L, Ames BN: Ascorbate is an outstanding antioxidant in human blood plasma. Proc Antl Acad Sci 86; 6377-6387, 1989.
13. Gaziano JM: Antioxidant vitamins ang coronary artery disease risk. Am J Med Sep 26. 97 (3a): 18-28. 1994.
14. Gey KF: Lipids, lipoproteins and antioxidants in cardiovascular dysfunction. Biochemical Society Transaction 18: 1041-1045, 1986.
15 Gey KF: On the antioxidant hypothesis with regard to arteriosclerosis. Bibl Nutr Diet 37;53-91. 1991.
16. Gilligan DM, Sack MN, Guetta V. Casino PR, Quyyumi AA. Rader Dj, Panza JA. Cannon RJ: Effect of antioxidant vitamins on LDL oxidation and impaired endothelium-dependent vasodilation in patients with hypercholesterolemia. J Am Coll Cardiol 24 (7): 1611-7, 1994.
17. Hallfrisch J, Singh UN, Muller DC, Baldwin H,, Bannon ME, Andreas R: High plasma vitamin C associated with high plasma HDL and HDL2 cholesterol. Am J Clin Nutr 60:100-5, 1994.
18. Hicks Al, Mac Dougall JD, Muckle TJ: Acute changes in HDL-C with exercise of different intensities. J Appl Physiol 63:1956-1960, 1987.
19. Hubinger LM, Mackinnon LT; The acute effect of 30 min of moderate exercise on HDL-C in untrained middle-aged men. Eur J Appl Physiol 65:555-560,, 1992.
20. Jacques PF. Sulsky SI, Perrone GA, Schaefer EJ: Ascorbic acid and plasma lipids. Epidemiology 5: 10-26, 1994.
21. Jacques PF, Sulsky SI, Perrone GA, Schaefer EJ: Effect of vitamin C supplementation on lipoprotein cholesterol apoliportein and triglyserid concentrations. Ann Epidemiology 5; 52-59, 1995.
22. Jialial I, Vega GL, Grunda SM: Physiologic levels of ascorbate inhibit the oxidative modification of LDL Atherosclerosis 82: 185-191, 1991.
23. Johnson GE, Obenshain SS: Nonresponsiveness of serum HDL-C to high dose ascorbic acid administration in
11
Spor Bilimleri Dergisi
normal men. Am J Clin Nutr 34: 2088-2091, 1981.
24. Khan AR, Seedarnee FA: Effect of ascorbic acid on plasma lipids and lipoproteins in healthy yong women. Atherosclerosis 39:89-95, 1981.
25. Kiens B, Lithell H; Lipoprotein metabolism influenced by trainig-induced changes in human skeletal mucsle. L Clin Invest 83: 538-564, 1989.
26. Lennon D, Stratman F, Francis £, Nagler J, Sharago E, Hanson P, Madden M, Spennetta T; TC and HDL-C changes during acute, moderate intensity exercise in men and women. Metabolism 32: 244-249, 1993,
27. Luc G. Fruchart JC: Oxidation of lipoproteins and atherosclerosis. Am J Clin Nutr 53:206 S- 209, 1991
28. Mackness Ml, Abbott C, Arrol S, Durnngton PN: The role HDL and lipid-soluble antioxidant vitamins in inhibiting LDL oxidation. Biochem J 294:829-834, 1993.
29. Morel DW, Moya M. Friday KE: Treatment of cholesterol-fed rabbits with dietary vitamins E and C inhibits lipoprotein oxidation but not development of arteriosclerosis. J Nutr 124 (11): 2123-2130, 1994.
30. Nikkila E, Taskinen M, Kekki M; Relation of plasma HDL-C to lipoprotein lipase activity in adipose tissue and.
31. Nutes GL, Sgoutas DS, Redden RA, Sigman SR, Gravinis MB, King SB, Berk BC: Combination of vitamin C and E alters the respons to coronary balloon injury in the pig. Arterioscler Thromb Vas Biol 15(1): 156-165, 1995.
32. Peterson VE, Crapo PA, Weininger J, Ginsberg H, Olefsky J: Quantification of plasma cholestrol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements. Am J Clin Nutr 28:548-557, 1975.
33. Riemersma RA, Wood DA, Macintyre CCA, Elton RA, Gey KF, Oliver MF: Risk of angina pectoris and plasma concentrations of vitamins A, C and E and carotene, Lancet 337: 1-5. 1991.
34. Salonen JT, Salonen R, lhanaine M, Parvianineb M, Seppanen R, Kantola M, Seppanen K, Rauramaa R: Blood pressure, dietary fats, and antioxidants. Am J Clin Nutr 48: 1226-1232, 1984
35. Simon JA: Vitamin C and cardiovascular disease: A review. J Am coll Nutr 11:107-125, 1992.
36. Slattery ML, Jacobs DR, Dyer A, Benson J, Hilner Je, Caan BJ: Dietary Antioxidant and plasma lipids: the car¬dia study. J Am Coll Nutr 14 (6): 635-642, 1995.
37.Steiner M: Effect of alpha-tocopherol administration on platelet funtion in man. Thromb Haemostas 43: 73-77, 1983.
38. Spittle CR: Atherosclerosis and vitamin C, Lancet 1280-1281, 1971.
39. Swan R, Kaplan B: Vitamins as therapy in the 1990 s. J Am Board Fam Pract 8(3): 206-16, 1995.
40. Steingerg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL: Beyond cholesterol. Modifications of LDL that increase its arterogenicity. N Eng J Med 320: 915-924, 1989.
41 .Tall AR, Small DM: Plasma HDL Lipoproteins. N Engl J Med 229:1232-1236, 1978.
42. Tan MH, Errol MD, Wilmshurst G, Gleason RE, Soldner JS; Effect of postyre on serum lipids. N Engl J Med 289; 416-419, 1973.
43. Thompson P, Cullinane E, Henderson L, Herbert P; Acute effects of prolonged exercise on serum lipids. Metabolism 29; 662-665, 1980.
44. Tran ZV, weltman A, Glass GV, Mood DP; The effects of exercise on blood lipids and lipoproteins: a metaanalysis studies. Med Sci Sports Exerc 415: 393-402, 1983.
45. Todd S, Woodward M, Bolton SC: An investigation of relationship between antioxidant vitamin intake and coronary heart disease in men and women using logistic regression analysis. J Clin Epidemiol 48 (2): 307-316, 1995.
46. Trout DL: Vitamin C and cardiovascular risk factors. Am J Clin Nutr 53: 322S-325S, 1991.
47. Yoshioka M, Matsushita T, Chuman Y: Inverse association of serum ascorbic acid level and blood pressure or rate of hypertension in male adults aged 30-39 years. Int J Vitam Nutr Res 54: 343-347,1984.

Thank you for copying data from http://www.arastirmax.com