Buradasınız

Anasayfa » Content

Malignant transformation in an ovarian mature cystic teratoma: A Case Report

Malignant transformation in an ovarian mature cystic teratoma: A Case Report

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2012

Key Words:

Author Name
Abstract (2. Language): 
Germ cell tumors account for approximately 30% of all ovarian tumors. Ninety-five percent of germ cell tumors are dermoid cyst (mature cystic teratoma). Malignant transformation in a mature cystic teratoma of the ovary is a rare event, developing in 1 to 2 % of cases and is associated with a poor prognosis. The most common malignancy is squamous cell carcinoma (75%). In the present report, we describe a case of squamous cell carcinoma arising in a mature cystic teratoma. A 40 year old female presented with a mass in abdomen since 3-4 months, pain in abdomen & recent haematuria. Clinical examination, Ultrasound & CT scan were suggestive of ovarian tumor- solid cystic ovarian teratoma. Exploratory laparotomy with debulking surgery was done as the mass was adherent to the adjacent structures like bladder & uterus. Final histopathological diagnosis offered was squamous cell carcinoma arising in a mature cystic teratoma.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastirmax-malignant-transformation-ovarian-mature-cystic-teratoma-case-report.pdf
  • 5
432-435
  • Turkish

REFERENCES

References: 

1) Robert H. Young, Philip B. Clement, Robert E. Scully. Sex Cord – Stromal, Steroid Cell, & Germ Cell
Tumors of the Ovary. Chapter 55. In Sternberg’s Diagnostic Surgical Pathology.– 4th edition Vol 3; 2579-
2615.
2) F. Nogales, A. Talerman, R.A. Kubik-Huch, F.A.Tavassoli, M. Devouassoux-Shisheboran. Germ Cell
Tumors In World Heaath Organisation Classification of tumors, Pathology & Genetics of Tumors of the
Breast & Female Genital Organs. Edited by Fattaneh A. Tavassoli, Peter Devilee 2003; 163-175.
3) Rosai J. Female Reproductive System, Chapter 19. In: Rosai J, editor. Ackerman′s Surgical Pathology. 9th
ed., Vol 2 St Louis: Mosby; 2004 1649 - 1736.
4) Stamp GWH, McConnell EM. Malignancy arising in cystic ovarian teratomas - A report of 24 cases. Br J
Obstet Gynaecol. 1983; 90:671-675.
5) M.C. Anderson. Tumors of the ovary 4: germ cell tumors Chapter 20 In: Symmers St. W. C. Systemic
Pathology by 38 authors, Gynaecological Pathology: 2nd edition, 367-392.
6) Kikkawa F, Ishikawa H, Tamakoshi K, Nawa A, Suganuma N, Tomoda Y. Squamous Cell Carcinoma arising
from mature cystic teratoma of the ovary : A clinicopathologic analysis. Obstet Gynaecol. 1997; 89:1017 –
1022.
7) Siamak Shariat – Torbaghan MD, Mohsen Emami – Aleagha MD, Sanambar Sedighi MD, Farnoosh
Azadbakht MD, amir Keshvari MD, Behzad Hajarizadeh MD MPH, Juan Rosai MD. Squamous Cell
Carcinoma arising in an Ovarian mature cystic teratoma; A Case report. Arch Iranian Med 2009; 12(2): 186-
189.
8) Kikkawa F, Nawa A, Tamakoshi K, Ishikawa H, Kuzuya K, Suganuma N, et al. Diagnosis of Squamous Cell
Carcinoma arising from mature cystic teratoma of the ovary. Cancer. 1998; 82:2249 – 2255.
9) Bernard Czernobilsky, Beatriz Lifschitz – Mercer, Lawrence M. Roth. The ovary & Fallopian Tube Chapter
52. In: Principles and Practice of Surgical Pathology & Cytopathology. Steven G. Silverberg, 3rd ed. Vol. 3;
2525 – 2574.

Thank you for copying data from http://www.arastirmax.com