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“Diagnosis of severity of COPD on the basis of electrocardiogram”

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Abstract (2. Language): 
Introduction: One of the major cause of morbidity and mortality in India especially in rural areas is COPD (Chronic obstructive pulmonary disease). Diagnostics test for COPD is spirometry FEV1/FVC <0.7 and FEV1% Of Expected <80%. Spirometry is costly and is not readily available in rural settings whereas ECG is easily available, affordable, does not require patient’s conscious effort. This study was done to correlate significant ECG finding such as P pulmonale (peaked p wave in lead II) with the severity of COPD, to make the diagnosis of COPD easy. Methods: The present study consisted of 40 diagnosed patients of COPD on the basis of spirometry (FEV1/FVC) and 20 control cases. We did Chest X Ray PA view, spirometry and Standard 12 lead ECG. ECG was analysed for P Pulmonale, RVH, RBBB and LVH . Observation: Mean FEV1/FVC ratio for cases was 54.35 ± 9.90, mean FEV1 was 42.74. 55% patient were having severe airflow obstruction and out of these 86.36% have significant ECG changes. The Control group was not having any significant changes in ECG. Result: In present study changes in ECG were correlated with severe obstruction. In none of patients with non severe COPD, Ppulmonale was present. So, there are chances of false negative but not of false positives in detecting COPD cases by ECG. If P pulmonale is present it can be concluded that COPD is severe and patient may be managed accordingly even if spirometry is not available.
FULL TEXT (PDF): 
527-530

REFERENCES

References: 

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COPD was 86.36%, Specificity 100%, positive predictive
value 100%, negative predictive value 85.7%, Accuracy
92.5%.Statistical calculations was done by Microsoft
excel and Medcal.
Discussion:
Among 40 patients with COPD enrolled in the present
study, mean age of patients was 60.12 years. The
prevalence was higher among Muslims, belonging to
lower socio-economic status, as Muslim population is
dominant in this part of the state. All of the patients were
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correlated with severe obstruction as out of 22 patients
with severe COPD, 19 had changes in ECG in form of Ppulmonale.
In none of patients with non severe COPD, Ppulmonale
was present. So, there are chances of false
negative but not of false positives in detecting COPD cases
by ECG. If P pulmonale is present it can be concluded that
COPD is severe and patient may be managed accordingly
even if spirometry is not available. If P pulmonale is
present, patients may be started on both inhaled
corticosteroids as well as on inhaled long acting β2 agonist.
In many hospitals in India ECG facilities are available but
spirometry is not available, especially in rural areas which
contribute a large portion of population in India. ECG does
not require cooperation from patient, unlike spirometry. In
India it is often difficult for patients to understand how to
perform spirometry. Even after repeated attempts they are
not able to do it and this can lead to wrong diagnosis. Often
in the setting of ICU or in case of severe COPD, ECG may
be performed but not spirometry.
Indian Journal of Basic & Applied Medical Research; March 2013: Issue-6, Vol.-2, P. 527-530
530
www.ijbamr.com
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