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“Predictive value of absolute Eosinophil count for Bronchial Hyper reactivity in allergic rhinitis”

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Background: Allergic rhinitis patients are at risk of development of asthma. These patients may also have peripheral eosinophilia and bronchial hyper reactivity. The present study was aimed to evaluate the correlation and predictive value of peripheral blood eosinophilia for bronchial hyper reactivity (BHR) in patients with allergic rhinitis but without asthma. Methods: 41 Subjects with history of allergic rhinitis symptoms and peripheral eosinophilia but without asthma were tested for bronchial hyper reactivity with bronchial provocation test (BPT) with histamine. Absolute eosinophil count was estimated and correlated with degree of bronchial hyperreactivity . Results: Bronchial hyperreactivity was observed in 24 patients out of 34 with peripheral eosinophilia . Positive predictive value was 70.59 %[ 95% CI: 52.52 % to 84.88 %] . Conclusions: 71 % of allergic rhinitis patients with peripheral eosinophilia had bronchial hyperreactivity who are with significant risk of future development of asthma. Measures to retard the progression to asthma by environmental modification , pharmacotherapy including intranasal corticosteroids[7,8,9] are recommended in these patients.
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  • 6
623-628
  • English

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