Buradasınız

Anasayfa » Content

Comparative microanatomy of the normal skin with that of immunobullous condition

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Introduction: Immunobullous diseases have been a topic of interest for long because of its morbidity and mortality.Among all immunobullous diseases Pemphigus Vulgaris, Pemphigus Foliaceus and Bullous Pemphigoid are common. Methodology: The present study is directed to compare the microanatomy of normal skin with the skin affected by above mentioned three diseases. Observations: For this 98 cases were taken randomly. Among them 35 were Pemphigus Vulgaris, 38 were Pemphigus Foliaceus and 25 were Bullous Pemphigoid. Biopsy was done. Results: Great alteration of normal histology was observed after H & E staining and light microscopy. Conclusion: Thus by comparing the pathological slides with the normal slides one can easily diagnose the diseases.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon 1146-1152.pdf.pdf
  • 8
1146-1152
  • English

REFERENCES

References: 

1. Wolff K, Kibbi GA, Jr Mihm MC. Basic Pathologic Reactions of the Skin. In: Freedberg IM, Eisen AZ,
Wolff K, et al, eds. Fitzpatrick’s Dermatology in General Medicine. 6th edn, Mc-Graw Hill; 200; 30.
2. Chmurova N, Svecova D. Pemphigus vulgaris: a 11- year review. Bratisl Lek Listy. 2009; 110 (8): 500-3.
3. Bernard P. Bullous pemphigoid [Internet]. Orphanet Encyclopedia. May 2006. Available from:
http://www.orpha.net/data/patho/GB/uk-Bullous pemphigoid.pdf.
4. Mong-Shang L, Chang-Ling F, Valeria A et al. Desmoglein-1- specific T lymphocytes from patients with
endemic pemphigus foliaceus (fogo selvagem). J Clin Invest. 2000; 105 (2): 207-13.
5. Hong WU. Non infectious Vesicobullous & Vesiculopustular Diseases. In: Elder DE, Elenitsos R, Johnson
BL et al, eds. Lever’s Histopathology of the Skin. 9th edn, Philadelphia: Lippincott Wlliams & Wilkins;
2005; 255.
6. Chandrashekar M, Leena JB, Vijaya B, Sunila R & GV Manjunath. A clinicopathological study of
immunobullous leisons of the skin a 2 years study.Novel Science International Journal of Medical
Sciences.2012; 19-26.
7. Fernandez JC, Dharani JB, Desai SC. A study of 100 cases of pemphigus-clinical features. Indian J
Dermatol Venerol.1970;36(1):1-11.
8. Wojnarowska F, Venning VA & Burge SM. Immunobullous Diseases. In: Burn T, Breathnach S, Cox N et
al, eds. Rook’s Textbook of Dermatology. 7th edn, Oxford: Blackwell Science Ltd; 2004; 41.7- 41.8
9. Cohen LM, Skopicki DK, Harrist TJ, Clark WH.Jr. Non infectious vesicobullous and vesicopustular
diseases.In: Elder D, Elenitras R, Jawaesky C, Johnsob Jr.B, eds. Lever’s histopathology of skin. 8th ed,
Philadelphia. Lipincott Raven; 1997; 209-387.
10. Hoss DM, Shea CR, Grant Kels JM. Neutrophilic Spongiosis in Pemphigus. Arch Dermatol. 1996; 132:
315-8.
11. Borradori L, Bernard P. Vesicobullous Diseases. In: Bolognia JL, Jorizzo JL,Rapini RP, et al, eds.
Dermatology. 2nd edn, MOSBY Elsevier; 2008; 431.

Thank you for copying data from http://www.arastirmax.com