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Pigmented Villonodular Synovitis (PVNS) – A Case Report

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2014

Key Words:

Author Name
Abstract (2. Language): 
Pigmented villonodular synovitis (PVNS) is benign proliferative disorder of the synovium of unknown origin. PVNS is divided into intra-articular and extra-articular form which may present as i) diffuse or ii) localised/nodular form. It is commonly seen in knee joint but hip, ankle, shoulder, wrist & other joints can be involved. It is usually seen in young adults from 20-50 years of age. It is seen more in men than women. A 26 years old female presented to our OPD with chief complaints of pain & swelling over right knee since 1 year. MRI right knee was suggestive of synovial thickening & collection in anterior aspect of knee with peripheral hemosiderin deposits which is suggestive of PVNS. Arthroscopic resection of this lesion was performed & histological report was revealed presence of giant cells & hemosiderin laden macrophages which are suggestive of PVNS. The case is presented because of unusual involvement in a female. Milwaukee Shoulder Syndrome (MSS) may be associated with PVNS.
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