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Granular cell tumor: a report of two cases

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Abstract (2. Language): 
Granular cell tumor (GCT) is a rare neoplasm arising from skin, soft tissue and internal organs. It is hypothesized to be originating from the Schwann cells. It is usually benign but rarely malignant. The tumor is diagnosed by microscopic examination and can simulate any adnexal or soft tissue neoplasm. We report our findings in two cases, presenting with GCT of soft tissue. Nervous tissue elements were seen in both. The diagnosis was based on the characteristic tumor cells on Hematoxylin and Eosin stain (H & E) and confirmation of the neural origin required S-100 and NSE immuno-histochemistry.
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