Journal Name:
- Indian Journal of Basic & Applied Medical Research
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Abstract (2. Language):
Kikuchi-Fujimoto disease or Histiocytic necrotizing lymphadenitis is a benign, self limiting condition with higher prevelance in
Asians especially Japanese. Though the etiology of this disease remains
unknown, viral or autoimmune origin of the disease has been suggested. It is clinically characterized by lymphadenopathy, fever,
skin rashes/ erythema, and other systemic manifestations like diarrhea, vomiting, sore throat, arthralgia, myalgia and hepatosplenomegaly.
Laboratory findings are usually non-specific and Kikuchi disease is generally diagnosed based on characteristic
histopathological findings of the involved lymphnode. Its recognition is very important as one of the close differentials is a
systemic lupus erythematosis or a malignant lymphoma. Clinicians and pathologists knowledge of the disease helps prevent
misdiagnosis and provide appropriate treatment to the patients. Here we present a case of a young teenaged girl presenting with a
tender right cervical lymphadenopathy and fever. A diagnosis was made on biopsy after repeated aspirations and clinical
management strategies could not establish any diagnosis.
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