Journal Name:
- Indian Journal of Basic & Applied Medical Research
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Abstract (2. Language):
Background: Malaria continues to be a major public health problem in South East Asia. . Plasmodium
vivax is the most widely distributed human malaria parasite with an at-risk population of 2.5 billion
persons. With the implementation of molecular diagnosis, it has become evident that P.vivax
monoinfect ion could also result in multiple organ dysfunction and severe life-threatening disease as
seen in P. Falciparum infection.
Materials and Methods: A prospective study was conducted over a period of one and half years on
100 patients with severe malaria infected either with p.vivax or p.falciparum admitted in J.J.M
Medical college , Davangere .
Observation and Results: Out of 100 patients with severe malaria of which 65(65%) patients had
severe vivax and 35(35%) patients had severe falciparum malaria. Amongst vivax group, 43 (66.15%)
were males and 22(33.84%) females. Thrombocytopenia (89.23%) was the most common complicat ion
followed by hepatic (29.23), renal (7.69%) cerebral (4.61%) and pulmonary (3.07%) involvement.
Most patients were in the age group of 21-30 years .The mortality observed in severe vivax malaria
was 1.53% (1/65), as compared to falciparum malaria where it was 5.71% (2/35).
Conclusion: Severe malaria is usually caused by P. Falciparum but it has been observed in our study
that P.vivax malaria, which was considered to be a benign malaria, can also result in severe disease.
Thrombocytopenia is very common in severe vivax infection. Also, renal, hepatic, lung and cerebral
involvement are also affected.
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