Buradasınız

Anasayfa » Content

Optical coherence tomography assisted macular thickness profile in high myopia

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2015

Key Words:

Author Name
Abstract (2. Language): 
Aims: To study the correlation of high myopia with macular thickness by optical coherence tomography. Methods and Material: The macular thickness of 50 highly myopic eyes and 40 control (emmetropic) eyes from a north Indian patients was measured using the Fourier domain optical coherence tomography (FD OCT). All highly myopic patients selected for the study had a spherical equivalent of > -6.0D and IOP <21 mmHg. None of the patients included in the study had evidence of concomitant ophthalmic disease and none had undergone refractive surgery. Results: The overall mean macular thickness in the myopic groups and control were 262.98 (±24.98) μm and 290.92 (±11.54) respectively. The total macular thickness was less in myopic eyes as compared to emmetropic eyes. But in contrast, the central foveal thickness was 265.43 (±32.69) μm in myopes and 235.95(±21.91) μm in emmetropes. The para and peri foveal retinal thickness was significantly thin in myopic eyes as compared to emmetropic eyes. Whereas central foveal thickness more in the myopes. Conclusions: Total macular thickness was significantly decreased in myopic eyes as compared to emmetropic eyes. However central (foveal) thickness was significantly high in high myopes as compared to emmetropes. Central foveal thickness increase in high myopes may be confused with retinoschisis / retinal edema. There is therefore a need to have a macular thickness normogram for high myopes of a given population group to avoid wrong interpretation.
Bookmark/Search this post with
FULL TEXT (PDF): 
PDF icon arastirmax-optical-coherence-tomography-assisted-macular-thickness-profile-high-myopia.pdf
  • 2
159
166
  • English

REFERENCES

References: 

1. Lim MC, Hoh S, Foster PJ, et al. Use of optical coherence tomography to assess variations in macular
retinal thickness in myopia. Invest Ophthalmol Vis Sci 2005; 46:974–8.
2. Ho T, Shih Y, Lin S, Lin LL, Chen M. Peculiar arcuate scotoma in pathologic myopia-optical
coherence tomography to detect peripapillary neural tissue loss over the disc crescent. Graefes Arch
Clin Exp Ophthalmol 2005; 243:689–94.
3. Leung CK, Mohamed S, Leung KS, et al. Retinal nerve fiber layer measurements in myopia: an optical
coherence tomography study. Invest Ophthalmol Vis Sci 2006; 47:5171–6.
4. Choi S, Lee S. Thickness changes in the fovea and peripapillary retinal nerve fiber layer depend on the
degree of myopia. Korean J Ophthalmol. 2006; 20:215–9.
5. Hoh S, Lim MC, Seah SK, et al. Peripapillary retinal nerve fiber layer thickness variations with
myopia. Ophthalmology 2006; 113:773–7.
6. Yanoff M, Fine BS. Ocular Pathology: A Text and Atlas. Harper & Row Philadelphia. 1982; 513–514.
7. Spencer WH. Ophthalmic Pathology: an Atlas and Textbook. WB Saunders Philadelphia 1985; 3rd
ed.395–400.
8. Curtin BJ, Karlin DB. Axial length measurements and fundus changes of the myopic eye. Trans Am
Ophthalmol Soc. 1970; 68:312–334.
9. Wakitani Y, Sasoh M, Sugimoto M, et al. Macular thickness measurements in healthy subjects with
different axial lengths using optical coherence tomography. Retina. 2003; 23:177–182.
10. Zou H, Zhang X, Xu X, et al. Quantitative in vivo retinal thickness measurement in Chinese healthy
subjects with the retinal thickness analyzer.Invest Ophthalmol Vis Sci. 2006; 47:341–347.
11. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991; 254:1178–1181.
165
Indian Journal of Basic and Applied Medical Research; March 2015: Vol.-4, Issue- 2, P. 159-166
162
www.ijbamr.com P ISSN: 2250-284X , E ISSN : 2250-2858
12. Tewari HK, Wagh VB, Sony P, Venkatesh P, Singh R. Macular thickness evaluation using the optical
coherence tomography in normal Indian eyes. Indian J Ophthalmol 2004; 52:199-204.
13. Pradhan ZS, Braganza A, Abraham LM: Determinants of macular thickness in normal Indian eyes.
Journal of Clinical Ophthalmology and Research ; 2013;1 (1):11-16.
14. Choovuthayakorn J, Watanachai N, Chaikitmongkol V, Patikulsila D, Kunavisarut P, Ittipunkul N:
Macular thickness measured by spectral-domain optical coherence tomography in healthy Thai eyes.
Japanese Journal of Ophthalmology; 2012; 56(6):569-74.
15. Chan A, Duker JS, Ko TH, Fujimoto JG, Schuman JS: Normal Macular Thickness Measurements in
Healthy Eyes Using Stratus Optical Coherence Tomography; Arch Ophthalmol. 2006
February; 124(2): 193–198.
16. Appukuttan B, Giridhar A, Gopalakrishnan M, Sivaprasad S: Normative spectral domain optical
coherence tomography data on macular and retinal nerve fiber layer thickness in Indians; Indian journal
of ophthalmology;2014, 62(3):315-321.
17. Adhi M, Aziz S, Muhammad K, Adhi MI: Macular Thickness by Age and Gender in Healthy Eyes
Using Spectral Domain Optical Coherence Tomography; PLoS ONE | www.plosone.org ; 2012;7 (5)
:1-6.
18. Al-Haddad C, Barikian A, Jaroudi M, Massoud V, Tamim H, Noureddin B: Spectral domain optical
coherence tomography in children: normative data and biometric correlations; BMC Ophthalmology
2014, 14(53):1-8.
19. Ooto S, Hangai M, Sakamoto A,Tomidokoro A, Araie M, Otani T, et al. Three-Dimensional Profile of
Macular Retinal Thickness in Normal Japanese Eyes; IOVS, 2010, 51(1):465-473.
20. Dennis Shun Chiu Lam, Leung SK, Mohamed S, Chan W, Palanivelu MS, Cheung CY et al. Regional
variation in the relationship between macular thickness measurements and myopia. The association for
research in vision and ophthalmology,Inc.2006;
21. P C Wu, Y J Chen, C H Chen, Y H Chen, S J Shin H J Yang et al. Assessment of macular thickness
and volume in normal eyes and highly myopic eyes with third generation optical coherence
tomography.2007:551-555
22. Mrugacz M, Bakunowicz-Lazarczyk A, Sredzinska-Kita D. Use of optical coherence tomography in
myopia. J Peads Ophthalmol Strabismus. 2004; 41:159–162.

Thank you for copying data from http://www.arastirmax.com