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Etiological profile of neonatal hyperbilirubinaemia in the rural area of Rajasthan

Journal Name:

  • Indian Journal of Basic & Applied Medical Research

Publication Year:

  • 2015

Key Words:

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Abstract (2. Language): 
Introduction: Jaundice is most common problem faced by neonates in the first few week of life. The aim of the study is to find out the etiology of hyperbilirubinemia in neonates admitted in neonatal intensive care unit and post natal ward in a tertiary care hospital. Methods: This Observational study was conducted in Neonatal Intensive Care Unit (NICU) and Post Natal Ward in NIMS Medical College & Hospital, Shobha Nagar, Jaipur.(Rajasthan),after approval from the hospital ethical committee , over a period of 12 months (May 2013 to April 2014). Study was carried on 250 neonates presenting clinically with neonatal hyperbilirubinemia. Results: The onset of jaundice was seen maximum between live hour 24-72 hours (n=145, 58% cases), followed by live hour 72 hours-14 days (n=80, 32%). At more than 2 weeks there was only 1 case (0.4%). The etiological factors in the causation of jaundice in the decreasing order of frequency were Physiological (28%), ABO incompatibility (24.4%), Rh incompatibility (13.6%), Idiopathic (10.4%), Cephalhematoma (10.4%), Septicemia (6%), IUI (4%), BMJ (2%), G6PD deficiency (0.8%), and Galactosemia (0.4%).As per the gestational age, physiological jaundice was more common in the healthy full term babies. ABO and Rh incompatibility were more common in the preterm babies. Cephalhematoma was more common in full term babies. Moreover cephalhematoma was associated with H/o of induced labour with oxytocin in 3 cases. Conclusion: All newborn babies presenting with neonatal jaundice should be promptly investigated to search for underlying treatable conditions.
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REFERENCES

References: 

1. Jaundice and hyperbilirubinemia in the newborn. In: Kliegman RM, Stanton BF, St. Geme JW et al, eds.
Nelson Textbook of Paediatrics. 19th ed. Philadelphia: Saunders, 2012: 603-12.
2. Porter ML and Dennis BL. Hyperbilirubinemia in Term Newborn. American Family Physician 2002, vol-
65, 599-606.
3. Maisels MJ, Clifford K, Antle CE. Jaundice in the healthy newborn infant: a new approach to an old
problem. Pediatrics 1988; 81: 505-511.
4. Kiviahan C, Jams EJ. The natural history of neonatal jaundice. Paediatrics 1984; 74: 364-370.
5. Connoly AM Volpe et al. clinical features of bilirubin encephalopathy. perinatal 1990, June 17, Vol
17,371-379.
6. Kramer LI. Advancement of dermal icterus in the jaundiced newborn. Am J Dis Child 1969; 118:454-8.
7. Moyer VA, Ahn C, Sneed S. Accuracy of clinical judgment in neonatal jaundice. Arch Pediatr Adolesc
Med 2000; 154: 391-394.
8. Ebbensen, Hansen et al. recurrence of icterus in term and near term infants, Denmark, Acta pediatrica 2007,
V-89, issue-10, 1213-1217.
231
Indian Journal of Basic and Applied Medical Research; March 2015: Vol.-4, Issue- 2, P. 223-232
224
www.ijbamr.com P ISSN: 2250-284X , E ISSN : 2250-2858
9. Melton K, Akinkbi HT, Neonatal jaundice. Strategies to reduce bilirubin induced complications. Postgrad
Med 1991, 106:167-8,171-4, 177-8.
10. Clemons RM. Issues in newborn care. Prim Care 2000;27:251-67
11. Effiong CE et al. Neonatal jaundice in Ibadan. Incidence and etiologic factors born in hospital, Nigeria.
Journal of National Medical Association 1975; 67, No-3: 208-210.
12. Narang A, Ghatwala G, Kumar P et al. Neonatal jaundice, an analysis of 551 cases. Indian paediatrics
1996; 34:429-32.
13. Korejo H et al. Risk facors for kernicterus in neonatal jaundice, Karachi, Pakistan. GJMS 2010; 8, No-1.
14. Bhutani VK. Evidence based issues regarding neonatal hyperbilirubinemia. Pediatrics review 2005;
114:130-153.
15. Bajpai PC, Mishra PK, Agarwal M et al. An etiological study of neonatal hyperbilirbinemia. Indian J
Pediatr 1971; 38: 424-429.
16. Onyearugha CN, Onyire BN, Ugboma HAA. Neonatal Jaundice: prevalence and associated factors as seen
in Federal Medical Centre Abakaliki, Southeast Nigeria. Journal of clinical medicine and research; 3(3):
40-45.
17. Singhal PK, Singh M, Paul VK, Deorari AK, Ghorpade MG. Spectrum of neonatal hyperbilirubinemia: An
analysis of 454 cases. Indian Pediatr 1992; 29:319-325.
18. Hussain Bux, Ghulam et al. Risk factors for kernicterus in neonatal Jaundice. GJMS 2010; 8: 12-14.
19. Anand JS, Magotra ML. Neonatal jaundice-its incidence and etiology. Indian paediatr 1978;15:155-160.
20. Bahl L, Sharma R, Sharma J et al, etiology of neonatal jaundice at Shimla. Indian paediatrics 1994;
31:1275-78.
21. Merchant RH, Merchant SM, Babar ST. A study of 75 cases of neonatal jaundice. Indian Pediatr 1975, 12:
889-893.
22. Bedowra et al. Risk factors and outcome of neonatal jaundice in a tertiary hospital. Medical journal 2010;
4(2): 70-3.
23. Suwimol et al. Exchange transfusion and its morbidity in 10 yrs period at King Chulalongkorn hospital.
Thailand 2005; 88(5): 588-592.
24. Joshi BD, Singh R, Mahato D et al. Clinico-laboratory profile of neonatal hyper-bilirubinemia in term
babies at B.P. Koirala institute of health science, Dharan, Nepal, JNHRC 2004; 2:30-32.
25. Sgro M, Campbell D, Shah V. Incidence and causes of severe neonatal Hyperbilirubinemia in Canada.
CMAJ 2006; 175(6): 587-90.
26. Heydarian F, Majdi M. Severe Neonatal Hyperbilirubinemia; Causes and Contributing Factors Leading to
Exchange Transfusion at Ghaem Hospital in Mashhad. Acta Medica Iranica 2010; 48 (6): 399-402.
27. Joshi BD, Singh R, Mahato D et al. Clinico-laboratory profile of neonatal hyper-bilirubinemia in term
babies at B.P. Koirala institute of health science, Dharan, Nepal, JNHRC 2004; 2:30-32.
28. Sgro M, Campbell D, Shah V. Incidence and causes of severe neonatal Hyperbilirubinemia in Canada.
CMAJ 2006; 175(6): 587-90.

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