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Blastocystosisli Hastalarda Lipid Peroksidaz Seviyesi

Lipid Peroxidation Level in Patients with Blastocystosis

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Abstract (2. Language): 
Aim: To investigate the oxidative stress hypothesis in patients infected with Blastocystis hominis. Method: Serum malondialdehyde concentration activity was measured in 52 patients who were positive for intestinal parasite of Blastocystis hominis. Scores were obtained for the positives and their age-and sex-matched 60 Blastocystis hominis negative healthy controls. For comparison of two groups of continuous variables, independent samples t-test was used. Results: There were no significant difference between malondialdehyde levels of patients with Blastocystis and control group both for females (p>0.05) and males (p>0.05). In addition, in the patient and control group, no correlation was found between age and malondialdehyde levels (p>0.05) both in females and males. Conclusion: No change was observed in malondialdehyde levels in the patients with Blastocystis compared to controls.
Abstract (Original Language): 
Amaç: Blastocystis hominifXe enfekte hastalarda oksidatif stres hipotezinin incelenmesi. Metod: Serum malondialdehid konsantrasyon aktiviteleri 52 Blastocystis hominis pozitif hastada ölçüldü. Elde edilen sonuçlar yaş ve cinsiyete göre 60 kontrol ile karşılaştırıldı. Grupların karşılaştırılmasında bağımsız t-testi kullanıldı. Bulgular: Kontrol grubu ile Blastocystis hominis ile enfekte hastalarda malondialdehid seviyelerinde istatistiksel olarak hem erkeklerde hem de bayanlarda bir fark bulunmadı. Aynı zamanda yaş ve malondialdehid seviyeleri arasında hem erkeklerde hem de bayanlarda kontrol grubu ile Blastocystis hominis ile enfekte hastalarda bir fark gözlenmedi. Sonuç: Blastocystis hominifXe enfekte hastalarda malondialdehid seviyelerinde kontrol grubuna göre bir değişiklik gözlenmedi.
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REFERENCES

References: 

1. Zierdt CH, Zierdt WS, Nagy B. Enzyme-linked immunosorbent assay for detection of serum antibody to Blastocystis hominis in symptomatic infections. Journal Parasitology, 1995; 81:127-129.
2. Shlim DR, Hoge CW, Rajah R, Rabold JG, Echeverria P. Is Blastocystis hominis a cause of diarrhea in travellers? A prospective study in Nepal. Clinical Infectious
Disease,1995; 21:97-101.
3. Markell EK, Udkow MP. Blastocystis hominis: pathogen or fellow traveler? American Journal Tropical Medicine and Hygiene. 1986; 35: 1023-1026.
4. Albrecht H, Stellbrink HJ, Koperski K, Greten H. Blatocystis hominis in human immunodeficieny virus-related diarhea. Scand J Gastroenterol, 1995; 302: 909¬914.
5. Nayak DU, Karmen C, Frishman WH, Vakili BA. Antioxidant vitamins and enzymatic and synthetic oxygen-derived free radical scavengers in the prevention and treatment of cardiovascular disease. Heart Disease, 2001; 3: 28-45.
6. Draper HH, Hadley M. A review of recent studies on the metabolism of exogenous and endogenous malondialdehyde. Xenobiotica, 1990; 20: 901-907.
7. Romero FJ, Bosch-Morell F, Romero MJ, Jareno EJ, Romero B, Marin N et al. Lipid peroxidation products and antioxidants in human disease. Environmental
Health Perspectives, 1998; 106: 1229-1234.
8. Jareno EJ, Bosch-Morell F, Fernandez-Delgado R, Donat J, Romero FJ. Serum malondialdehyde in HIV-seropositive children negatively correlates with CD4+
lymphocytes count. Biofactors, 1998; 8: 129-132.
9. Sonnerborg A, Carlin G, Akerlund B, Jarstrand C. Increased production of malondialdehyde in patients with HIV infection. Scandınavıan Journal of Infectıous Dıseases, 1988; 20: 287-290.
10. Yazar S, Hamamcı B, Birhan M, Şahin I. The distribution of intestinal parasites in patients applied to coprology laboratory of Parasitology department of Erciyes University, Medical Faculty. Acta Parasitologica Turcica, 2001; 25: 53-55.
11. Jain SK, Evidence for membrane lipid peroxidation during the in vivo aging of human erythrocytes. Biochem Biophys Acta, 1988; 937; 205-210.

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