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Turgut Özal Tıp Merkezinde Ameliyat Olan Hastalarda Serum Kolinesteraz Aktiviteleri

Serum Cholinesterase Activity in Operated Patients in Turgut Özal Medical Center

Journal Name:

  • İnönü Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Aim: The aim of this study was to determine distribution of serum cholinesterase activity according to age and sex and serum cholinesterase activity of patients who were operated in Malatya Turgut Ozal Medıcal Center. Material and Method: In this study, serum cholinesterase activity of 96 (44.2%) male and 121 (55.8%) female patients who were operated in Turgut Özal Medical Center was determined by enzyme-spectrophotometric method. Results: Enzyme activities were 7092+226 U/ml and 6804+207 U/ml in males and females, respectively (p=0.58). The enzyme activity in the 0-15 years age group (8680+525 U/ml) was significantly higher that in the over 41 years age group (6567+330 U/ml) of males (p=0.01). However, there were no significant differences among age groups in females (p=0.06). The enzyme activity in the 16-40 years age group of females (6335+308 U/ml) was significantly lower that in the 16- 40 years age group (7316+334 U/ml) of males (p=0.04). Enzyme activity was found to be under the normal range (<4100 U/ml) in 10.6% of patients (8.3% for males, 12.4% for females). Conclusion: In conclusion, it may be more important to measure the serum cholinesterase activity before surgery in the over 41 years age group of males and in the 16-40 years age group of females.
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Abstract (Original Language): 
Amaç: Malatya Turgut Özal Tıp Merkezi'ne ameliyat olmak için başvuran hastalarda, serum kolinesteraz düzeylerini ve enzim düzeylerinin yaş ve cinsiyete göre dağılımını belirlemektir. Materyal ve Metod: Bu çalışmada, Turgut Özal Tıp Merkezi'nde ameliyat olan, 96 (%44.2) erkek ve 121 (%55.8) kadın hastanın serum kolinesteraz aktiviteleri enzim-spektrofotometrik yöntemle tayin edildi. Bulgular: Enzim düzeyi, erkeklerde 7092+226 U/ml, kadınlarda 6804+207 U/ml olarak bulundu (p=0.58). 0-15 yaş grubu erkek hastalardaki enzim aktivitesi (8680+525 U/ml), 40 ve üzeri yaş grubuna (6567+330 U/ml) göre anlamlı düzeyde yüksekti (p=0.01). Kadınlarda ise, yaş grupları arasında anlamlı bir fark bulunmadı (p=0.06). Yaş gruplarında; 16-40 yaş grubu kadın hastalardaki enzim aktivitesi (6335+308 U/ml), 16-40 yaş grubu erkek hastalara (7316+334 U/ml) göre anlamlı düzeyde düşüktü (p=0.04). Tüm hastaların %10.6'sında enzim düzeyi normal sınırların altında (<4100 U/ml) idi. Bu oran, erkeklerde %8.3, kadınlarda ise %12.4 olarak bulundu. Sonuç: Özellikle 41 yaş ve üzerindeki erkeklerde ve 16-40 yaş grubu kadınlarda anestezi öncesinde serum kolinesteraz düzeyinin ölçülmesi daha anlamlı olabilir.
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  • 4
191-193
  • Turkish

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